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Autor:
Kjetil Taskén, Sven Enerbäck, Line M. Grønning, Miles D. Houslay, George S. Baillie, Martin J. Lynch, Anna Cederberg
Publikováno v:
FEBS Letters. 580:4126-4130
Overexpression of forkhead transcription factor FOXC2 in white adipose tissue (WAT) leads to a lean phenotype resistant to diet-induced obesity. This is due, in part, to enhanced catecholamine-induced cAMP-PKA signaling in FOXC2 transgenic mice. Here
Publikováno v:
FEBS Letters. 580:1509-1514
Different C-terminal fragments of parathyroid hormone (PTH)-(1–84) in blood participate in the regulation of calcium homeostasis by PTH-(1–84), and an antagonizing effect for the large carboxyl-terminal parathyroid hormone (C-PTH)-fragment (7–8
Autor:
Helmut Geiger, Albrecht Piiper, Martina Herrero, Ulrich F. Mondorf, Ernst H. Scheuermann, Michael Bender
Publikováno v:
FEBS Letters. 441:205-208
Evidence suggests an important role of elevated serum lipoproteins in the progression of renal glomerulosclerosis. We report here that lipoprotein (a) (Lp(a)) increased phosphorylation and activity of mitogen activated protein kinase (MAPK) in human
Publikováno v:
FEBS Letters. 418:287-290
The effects of the novel vasoactive regulatory peptide, adrenomedullin, on human oral keratinocytes was investigated. Adrenomedullin, acting via its specific receptor, stimulated a dose-dependent increase in DNA synthesis, and, in addition, stimulate
Autor:
Shinji Kosugi, Toru Mori
Publikováno v:
FEBS Letters. 341:162-166
We investigated the role of the 1st cytoplasmic loop of the thyrotropin receptor (TSHR) on signal transduction using mutants as we did the 2nd and 3rd cytoplasmic loops [Kosugi S. et al. (1994) Mol. Endocrinol., in press; and 7, 1009-1020]. Five subs
Publikováno v:
FEBS Letters. 315:134-138
Using a variety of peptide analogues of oxytocin (OT) and Arg8-vasopressin (AVP), OT-mediated induction of urokinase-type plasminogen activator (uPA) was examined in LLC-PK1 renal epithelial cells, which possess distinct high-affinity receptors of bo
Autor:
Kerstin Leuthäuser, Walter Born, Nicole Bühlmann, Roman Muff, Steven M. Foord, Jan A. Fischer
Publikováno v:
FEBS Letters. 441:366-368
In Xenopus oocytes with an endogenous calcitonin gene-related peptide (CGRP) receptor, a receptor activity modifying protein (RAMP1) enhancing CGRP stimulated chloride currents of the cystic fibrosis transmembrane regulator was recently cloned [McLat
Autor:
Gernot Zissel, Tomohiro Yano, Sung Jae Shin, Tomio Ichikawa, Haruna Satoh, Joachim Muller-Qernheim
Publikováno v:
FEBS letters. 518(1-3)
Prostaglandin E2 (PGE2)-dependent effects on various cell responses are regulated by respective PGE2 receptors (EP1, EP2, EP3, EP4) expressing in target cells. Alveolar type II cell (a main progenitor cell of lung adenocarcinoma) expressed only EP4,
Publikováno v:
FEBS letters. 432(1-2)
Preproadrenomedullin, the precursor of proadrenomedullin N-terminal 20 peptide (PAMP), is produced by rat zona glomerulosa cells. The actions of PAMP on the rat adrenal have been investigated. PAMP was found to stimulate aldosterone secretion and cAM
Publikováno v:
FEBS letters. 397(1)
Angiotensin II (Ang II), a potent hypertrophic factor for vascular smooth muscle cells (VSMC), induces activation of the ras proto-oncogene product (Ras) and mitogen-activated protein (MAP) kinases, and tyrosine phosphorylation of a focal adhesion-as