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pro vyhledávání: ''
Autor:
Marios P. Stavridis, Mehmet Gundogdu, Sergio G. Bartual, Daan M. F. van Aalten, Andrew T. Ferenbach, Riina Žordania, Katrin Õunap, Veronica M. Pravata, Monica H. Wojcik, Sander Pajusalu
Publikováno v:
Febs Letters
'FEBS Letters ', vol: 594, pages: 717-727 (2020)
'FEBS Letters ', vol: 594, pages: 717-727 (2020)
X‐linked intellectual disabilities (XLID) are common developmental disorders. The enzyme O‐GlcNAc transferase encoded by OGT, a recently discovered XLID gene, attaches O‐GlcNAc to nuclear and cytoplasmic proteins. As few missense mutations have
Autor:
Etsuo Niki
Publikováno v:
FEBS Letters. 586:3767-3770
Oxidative modification of biologically essential molecules by reactive oxygen and nitrogen species (ROS/RNS) has been implicated in the pathogenesis of various diseases. At the same time, roles of ROS/RNS as physiological signaling messenger have bee
Autor:
Yeong-Jae Seok, Yangkyun Ryu, You-Jin Kim, Soon-Jung Park, Kyu-Ho Lee, Na Yeon Lee, Byoung-Mo Koo, Se-Jin Chun
Publikováno v:
FEBS Letters. 584:4537-4544
Vibrio vulnificus is an opportunistic human pathogen that causes severe infections in susceptible individuals. While the components of the Escherichia coli phosphoenolpyruvate: sugar phosphotransferase system (PTS) have been shown to regulate numerou
Autor:
Philippe Valet, Angelo Parini, Atul Pathak, Oksana Kunduzova, Céline Guilbeau-Frugier, Denis Calise, Camille Foussal, Olivier Lairez
Publikováno v:
FEBS Letters
FEBS Letters, 2010, 584 (11), pp.2363-70. ⟨10.1016/j.febslet.2010.04.025⟩
FEBS Letters, 2010, 584 (11), pp.2363-70. ⟨10.1016/j.febslet.2010.04.025⟩
International audience; Adipose tissue secretes a variety of bioactive factors, which can regulate cardiomyocyte hypertrophy via reactive oxygen species (ROS). In the present study we investigated whether apelin affects ROS-dependent cardiac hypertro
Autor:
Ashley Glumac, Jianfei Jiang, Natalia A. Belikova, Ruslan Rafikov, Valerian E. Kagan, Hülya Bayır, Joel S. Greenberger
Publikováno v:
FEBS Letters. 583:3437-3442
Manganese superoxide dismutase (MnSOD) is vital to the protection of mitochondria and cells against oxidative stress. Earlier, we demonstrated that catalytically active homo-tetramer of MnSOD can be stabilized by oxidative cross-linking. Here we repo
Autor:
Consuelo Borrás, Juan Gambini, Jose Viña, Alexander A. Boldyrev, Tatiana N. Fedorova, Sergey Stvolinsky, Raúl López-Grueso
Publikováno v:
FEBS Letters. 583:2287-2293
The validity of the free radical theory of aging has been recently questioned. Our aim was to test whether there is oxidative stress in tissues critically involved in accelerated aging (senescence-accelerated mice, SAM) and whether this correlates wi
Publikováno v:
FEBS Letters. 582:3893-3898
We have previously shown that homocysteine (Hcy) can induce monocyte chemoattractant protein-1 (MCP-1) secretion via reactive oxygen species (ROS) in human monocytes. Here, we show that Hcy upregulates expression of an important antioxidative protein
Publikováno v:
FEBS Letters. 579:3713-3717
Acyl-homoserine lactone (AHL) quorum sensing signals play a key role in synchronizing virulence gene expression in Pseudomonas aeruginosa, which could cause fatal bloodstream infections. We showed that AHL inactivation activity, albeit with variable
Autor:
Jacqueline London, Marie Le Pecheur, Bertrand Friguet, Evelyne Paly, Luc Farout, Emmanuel Bourdon
Publikováno v:
FEBS Letters. 579:3613-3618
Premature ageing, one of the characteristics of Down syndrome (DS), may involve oxidative stress and impairment of proteasome activity. Transgenic mice overexpressing the human copper/zinc superoxide dismutase (SOD1) gene are one of the first murine
Autor:
Jean Christophe Marvaud, Yannik Pereira, Mahmood Tavallaie, Maryse Gibert, Maria Manich, Stéphanie Raffestin, Alexandre Chenal, Daniel Gillet, Michel R. Popoff
Publikováno v:
FEBS Letters. 572:299-306
The botulinum neurotoxin A C-terminal fragment (Hc), which mediates the binding of the toxin to neuronal cell surface receptors, comprises two subdomains, Hc-N (amino acids 873–1095) and Hc-C (amino acids 1096–1296). In order to define the minima