Zobrazeno 1 - 10
of 16
pro vyhledávání: ''
Publikováno v:
FEBS Letters. 588:3427-3434
The present study explored the involvement of miR-302a in adipocyte differentiation via interaction with 3′-untranslated region of peroxisome proliferator-activated receptor gamma (PPARγ) mRNA. In differentiating 3T3-L1 adipocytes, expression of m
Autor:
Abu Asad Chowdhury, M. A. Mazid, Mitsuo Jisaka, Tsutomu Nagaya, Kohji Nishimura, Kohjiro Nagao, Kazushige Yokota
Publikováno v:
FEBS Letters. 580:6885-6890
15-Deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been identified as a natural ligand for peroxisome proliferator-activated receptor (PPAR) gamma to promote adipogenesis. However, it remains elusive about the ability of PPARgamma-expressing a
Autor:
Haruhiko Osawa, Takahiro Ogura, Naoto Kubota, Yan Tang, Tatsuya Nishimiya, Takashi Kadowaki, Hideichi Makino, Yasuo Terauchi, Hiroshi Onuma, Masaaki Ochi
Publikováno v:
FEBS Letters. 542:65-68
Phosphodiesterase 3B (PDE3B) gene expression is generally reduced in large adipocytes of obese, insulin-resistant mice. This reduced gene expression is restored by peroxisome proliferator-activated receptor (PPAR) gamma ligands accompanied by a reduc
Autor:
Viktor Magdolen, Sumito Sato, Achim Krüger, Horst Kessler, Wolfgang A. Schmalix, Bernd Muehlenweg, Manfred Schmitt, Charlotte Kopitz
Publikováno v:
FEBS Letters. 528:212-216
Urokinase-type plasminogen activator (uPA) binds with high affinity to its specific cell surface receptor (uPAR) (CD87) via a well-defined sequence within the N-terminal region of uPA (uPA(19-31)). Since this uPA/uPAR-interaction plays a significant
Autor:
Geoffrey Goldspink, Shi Yu Yang
Publikováno v:
FEBS Letters. 522:156-160
The physiological function of a recently cloned splice variant of insulin-like growth factor-I (IGF-I; mechano growth factor (MGF)) was studied using an in vitro cell model. Unlike mature IGF-I, the distinct E domain of MGF inhibits terminal differen
Autor:
Linda L. Demer, Simon Mark Jackson
Publikováno v:
FEBS Letters. 471:119-124
The reduced bone mineral density (BMD) observed in osteoporosis results, in part, from reduced activity of bone-forming osteoblasts. We examined the effect of peroxisome proliferator-activated receptor (PPAR) activators on MC3T3-E1 preosteoblast matu
Publikováno v:
FEBS Letters. 291:113-116
Expression of a transforming Ha-ras by dexamethasone in NIH3T3 cells transfected with a glucocorticoid-inducible Ha-ras construct results in a rapid desensitization of the intracellular Ca(2+)-mobilizing system to bombesin. This effect precedes the d
Publikováno v:
FEBS Letters. 267:85-88
Northern blot analysis demonstrated that the concentration of inositol 1,4,5-trisphosphate (IP3) receptor mRNA was greatest in cerebellar tissue. Moderate amounts of IP3 mRNA were present in brain tissue without cerebellum and tissue of the thymus, h
Publikováno v:
FEBS letters. 559(1-3)
To investigate the molecular events controlling reverse cholesterol transport, we compared gene expression of normal mouse liver to that of mice fed a long chain (LC) omega-3 fatty acid-enriched diet. Using cDNA microarrays, we assessed expression le
Autor:
Philippe Delerive, Giulia Chinetti, Christelle Faveeuw, François Trottein, Monique Capron, Véronique Angeli, Muriel Moser, Bart Staels, Josette Fontaine, Charlie Maliszewski, Philippe Gosset, Sylvie Fougeray
Publikováno v:
FEBS letters. 486(3)
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily. They are divided into three subtypes (alpha, beta or delta, and gamma) and are involved in lipid and glucose homeostasis and in the control of inflam