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Autor:
Abu Asad Chowdhury, M. A. Mazid, Mitsuo Jisaka, Tsutomu Nagaya, Kohji Nishimura, Kohjiro Nagao, Kazushige Yokota
Publikováno v:
FEBS Letters. 580:6885-6890
15-Deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been identified as a natural ligand for peroxisome proliferator-activated receptor (PPAR) gamma to promote adipogenesis. However, it remains elusive about the ability of PPARgamma-expressing a
Publikováno v:
FEBS Letters. 562:16-21
Abnormally high concentrations of beta-amyloid peptide (Abeta) and amyloid plaque formation in Alzheimer's disease (AD) may be caused either by increased generation or by decreased degradation of Abeta. Therefore, activation of mechanisms that lower
Autor:
Yasushi Furukawa, Hideyuki Sasaki, Masahiro Nishi, Takeshi Shimada, Takeshi Shono, Kishio Nanjo, Hiroto Furuta, Asako Doi, Ying Wang
Publikováno v:
FEBS letters. 584(8)
Ghrelin inhibits insulin secretion partly via induction of IA-2β. However, the orexigenic effect of ghrelin is mediated by the AMP-activated protein kinase (AMPK)–uncoupling protein 2 (UCP2) pathway. Here, we demonstrate that ghrelin’s inhibitor
Autor:
Roser Iglesias, Marta Giralt, Francesc Villarroya, Pilar Yubero, María Luisa Rodríguez de la Concepción
Publikováno v:
FEBS Letters. (7):1670-1674
Lithium impairs the appearance of the characteristic morphology of brown adipocytes and downregulates the expression of marker genes of brown adipocyte differentiation. These effects are dose-dependent and are more pronounced when exposure of preadip
Autor:
Mireille Donner, Philippe Valet, Nehmann Al-Makdissy, Mohamed Younsi, Evelyne Picard, Arnaud Bianchi, Nadine Martinet, Michel Dauça
Publikováno v:
FEBS Letters. (2-3):75-79
We recently demonstrated that the sphingomyelin (SM) content of adipocyte membranes was negatively correlated with the expression of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the subcutaneous adipose tissue of obese women with v
Autor:
Maria Teresa Maggiorella, Rosaria Varì, Beatrice Scazzocchio, Roberta Masella, Carmela Santangelo, Claudio Giovannini, Massimo D'Archivio, Carmela Filesi, Leonardo Sernicola
Publikováno v:
FEBS Letters. (15):2291-2298
The effect of oxLDL on CD36 expression has been assessed in preadipocytes induced to differentiate. Novel evidence is provided that oxLDL induce a peroxisome proliferator-activated receptor γ-independent CD36 overexpression, by up-regulating nuclear