Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joan J. Guinovart"'
Publikováno v:
FEBS Lett
Glycogen shortage during fasting coincides with dramatic changes in hepatic adenine nucleotide levels. The aim of this work was to study the relevance of liver glycogen in the regulation of the hepatic energy state during food deprivation. To this en
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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[EN] Both radiotherapy and most effective chemotherapeutic agents induce different types of DNA damage. Here we show that tungstate modulates cell response to DNA damaging agents. Cells treated with tungstate were more sensitive to etoposide, phleomy
Sodium tungstate activates glycogen synthesis through a non-canonical mechanism involving G-proteins
Publikováno v:
FEBS Letters. 587:291-296
Tungstate treatment ameliorates experimental diabetes by increasing liver glycogen deposition through an as yet unidentified mechanism. The signalling mechanism of tungstate was studied in CHOIR cells and primary cultured hepatocytes. This compound e
Autor:
J.J Caballero, María Dolores Suárez, Joan J. Guinovart, Rafael Salto, Alberto M. Vargas, M.D. Giron
Publikováno v:
FEBS letters. 542(1-3)
Oral administration of sodium tungstate is an effective treatment for diabetes in animal models. We examined the effects of 6 weeks of oral administration of tungstate on glucose transporters (GLUT) in streptozotocin-induced diabetic rat diaphragm. D
Publikováno v:
FEBS letters. 296(2)
2-Deoxyglucose and 5-thioglucose, in the same fashion as glucose, cause the inactivation of the rat hepatocyte glycogen phosphorylase and the activation of glycogen synthase. However, 6-deoxyglucose and 1,5-anhydroglucitol inactivate phosphorylase wi
Publikováno v:
FEBS letters. 290(1-2)
The mechanism by which yeast ras2 mutant hyperaccumulates glycogen has been investigated. Total glycogen synthase activity was between and 1.3 times higher in the ras2 mutant than in an isogenic strain. In addition, while in the normal strain the gly
Publikováno v:
FEBS Letters. 101:347-350
Publikováno v:
FEBS Letters. 200:47-50
Glucagon and epinephrine promote the inactivation of basal glycogen synthase in hepatocytes isolated from fed rats. However, this effect is only observable when the activation state of glycogen synthase is measured using the low glucose-6-P/high gluc
Publikováno v:
FEBS Letters. 129:123-126
Autor:
Joaquín Ariño, Josep Clotet, Isabel Fernández-Bañares, Friedrich K. Zimmmermann, Eckhard Boles, Josep M. Corominas, Joan J. Guinovart
Publikováno v:
FEBS Letters. (2):182-186
Disruption of the gene pgi1 of Saccharomyces cerevisiae , which codes for phosphoglucose isomerase, results in a dramatic increase in the amount of intracellular glycogen in early exponential cultures. The level or glucose 6-phosphate was much higher