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Publikováno v:
FEBS Letters. 591:527-539
Recent studies have revealed that the sensory nervous system is involved in bone metabolism. However, the mechanism of communication between neurons and osteoblasts is yet to be elucidated. In this study, we investigated the signaling pathways betwee
Publikováno v:
FEBS Letters. 589:1225-1233
Glycosylation plays a significant role in determining the receptivity of the uterine endometrium to embryo. Fucosyltransferase IV (FUT4) is expressed stage-specifically in the uterine endometrium of mammalians, and considered as a marker of the endom
Autor:
Alejandra Gorostizaga, Mercedes Mori Sequeiros García, Carlos F. Mendez, Cristina Paz, Andrea Acquier
Publikováno v:
FEBS Letters. 587:3254-3260
Intrarenally-produced dopamine (DA) induces a large increase in urinary sodium excretion mainly due to the inhibition of tubular sodium reabsorption. We aimed to study the participation of reactive oxygen species (ROS) in DA signaling pathway in prox
Autor:
Ali Zamani, Zhican Qu
Publikováno v:
FEBS Letters. 586:2360-2365
Serotonin, a known neurotransmitter, also functions as an angiokine to promote angiogenesis. The majority of serotonin in the human body is stored in platelets, and platelet aggregation leads to significant release of serotonin in thrombotic tumor en
Autor:
Su Peng, Xiaolin Ji, Muchen Xu, Xiaoyu Liu, Cheng Sun, Lan Luo, Lili Yao, Ningmei Shen, Meihong Wang, Kaixuan Li
Publikováno v:
FEBS letters. 589(24 Pt)
It has been reported that cystatin c (Cys C) closely correlates with metabolic disorders such as obesity and diabetes. However, it is still unknown whether Cys C plays a role for these disorders. Our results showed that the insulin signal transductio
Autor:
Abu Asad Chowdhury, M. A. Mazid, Mitsuo Jisaka, Tsutomu Nagaya, Kohji Nishimura, Kohjiro Nagao, Kazushige Yokota
Publikováno v:
FEBS Letters. 580:6885-6890
15-Deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been identified as a natural ligand for peroxisome proliferator-activated receptor (PPAR) gamma to promote adipogenesis. However, it remains elusive about the ability of PPARgamma-expressing a
Autor:
Alessandra Castegna, Iolanda Spera, Vittoria Infantino, Alessio Menga, Erika M. Palmieri, Vito Iacobazzi
Publikováno v:
FEBS letters. 588(24)
The role of glutamine synthetase (GS) during adipocyte differentiation is unclear. Here, we assess the impact of GS on the adipocytic response to a proinflammatory challenge at different differentiation stages. GS expression at the late stages of dif
Publikováno v:
FEBS letters. 588(13)
MicroRNAs have been shown to play an important role in insulin signaling but their biological function in insulin resistance induced by saturated fatty acids (SFA) remains largely unknown. Here, we report that SFA palmitate and high fat diet (HFD) si
Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor
Publikováno v:
FEBS Letters. 486:33-37
The leptin system provides a link between adipose mass and the central nervous system. The appetite suppressing effects of leptin are impaired in most obese patients and some mutant mice strains. Herein we describe how suppressor of cytokine signalli
Autor:
Valur Emilsson, Carolyn A. Lister, Michael A. Cawthorne, Jonathan R.S. Arch, Rolf P. de Groot
Publikováno v:
FEBS Letters. 455:170-174
Leptin concentrations are elevated in the majority of obese individuals raising the possibility that leptin resistance contributes to their obesity. Peripheral leptin administration for 48 h caused a several-fold increase in mRNA encoding the suppres