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Publikováno v:
FEBS Letters. 591:527-539
Recent studies have revealed that the sensory nervous system is involved in bone metabolism. However, the mechanism of communication between neurons and osteoblasts is yet to be elucidated. In this study, we investigated the signaling pathways betwee
Autor:
Alejandra Gorostizaga, Mercedes Mori Sequeiros García, Carlos F. Mendez, Cristina Paz, Andrea Acquier
Publikováno v:
FEBS Letters. 587:3254-3260
Intrarenally-produced dopamine (DA) induces a large increase in urinary sodium excretion mainly due to the inhibition of tubular sodium reabsorption. We aimed to study the participation of reactive oxygen species (ROS) in DA signaling pathway in prox
Publikováno v:
FEBS letters. 528(1-3)
The genetic defect in producing the adipose hormone leptin results among others in a drastic increase of bone mass. The current understanding is that under normal circumstances, osteoblast activity is indirectly suppressed by a hypothalamic relay ind
miR-96 promotes osteogenic differentiation by suppressing HBEGF–EGFR signaling in osteoblastic cells
Publikováno v:
FEBS Letters. (24):4761-4768
MicroRNAs (miRNAs) are a class of small non-coding RNAs with important roles in various biological and pathological processes, including osteoblast differentiation. Here, we identified miR-96 as a positive regulator of osteogenic differentiation in a