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Autor:
Marios P. Stavridis, Mehmet Gundogdu, Sergio G. Bartual, Daan M. F. van Aalten, Andrew T. Ferenbach, Riina Žordania, Katrin Õunap, Veronica M. Pravata, Monica H. Wojcik, Sander Pajusalu
Publikováno v:
Febs Letters
'FEBS Letters ', vol: 594, pages: 717-727 (2020)
'FEBS Letters ', vol: 594, pages: 717-727 (2020)
X‐linked intellectual disabilities (XLID) are common developmental disorders. The enzyme O‐GlcNAc transferase encoded by OGT, a recently discovered XLID gene, attaches O‐GlcNAc to nuclear and cytoplasmic proteins. As few missense mutations have
Autor:
Hideyuki Suzuki, Takafumi Mizushige, Hayato Aoki, Ryuhei Kanamoto, Kousaku Ohinata, Hiroshi Iwakura, Masaru Sato, Junya Nakato
Publikováno v:
FEBS Letters. 591:2121-2130
Ghrelin, an endogenous peptide isolated from the stomach, is known to stimulate food intake after peripheral administration. We found that the enzymatic digest of β-lactoglobulin decreases ghrelin secretion from the ghrelin-producing cell line MGN3-
Autor:
Kyoko Kuwahara-Arai, Taisuke Murakami, Hiroshi Tamura, Shin Yomogida, Akimasa Someya, Isao Nagaoka
Publikováno v:
FEBS Letters. 581:140-144
The action of antibacterial cathelicidin peptide CAP11 on the anandamide production from mononuclear phagocytes was examined. Lipopolysaccharide (LPS)-stimulation induced the anandamide production from macrophage-like RAW264.7, accompanied with the e
Autor:
Abu Asad Chowdhury, M. A. Mazid, Mitsuo Jisaka, Tsutomu Nagaya, Kohji Nishimura, Kohjiro Nagao, Kazushige Yokota
Publikováno v:
FEBS Letters. 580:6885-6890
15-Deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) has been identified as a natural ligand for peroxisome proliferator-activated receptor (PPAR) gamma to promote adipogenesis. However, it remains elusive about the ability of PPARgamma-expressing a
Publikováno v:
FEBS Letters. 579:4719-4723
Reactive nitrogen species and their by-products, such as peroxynitrite, modulate many physiological functions of skeletal muscle. Peroxynitrite generation occuring under specific conditions, such as inflammation, may also lead to skeletal muscle dysf
Publikováno v:
FEBS Letters. 579:3713-3717
Acyl-homoserine lactone (AHL) quorum sensing signals play a key role in synchronizing virulence gene expression in Pseudomonas aeruginosa, which could cause fatal bloodstream infections. We showed that AHL inactivation activity, albeit with variable
Autor:
Christiane Habich, Hubert Kolb, Volker Burkart, Ruurd van der Zee, Karina Kempe, Hill Gaston, Mark Lillicrap
Publikováno v:
FEBS Letters. 568:65-69
In the present study, we identified the human heat shock protein 60 (HSP60) epitope responsible for binding to macrophages. Studies using overlapping 15- and 20-mer peptides of the human HSP60 sequence to compete with binding of HSP60 to macrophages
Autor:
Miki Suzuki, Nobuyuki Takahashi, Yasutomi Kamei, Tomoyasu Taniguchi, Teruo Kawada, Osamu Ezaki, Shinji Miura, Junko Mizukami
Publikováno v:
FEBS Letters. 536:232-236
Lipoprotein lipase (LPL) plays a role in lipid usage in skeletal muscle by hydrolyzing plasma triglycerides into fatty acids, which are further utilized for β-oxidation. Lipid usage is stimulated during fasting, diabetes mellitus and exercise, conco
Autor:
Geoffrey Goldspink, Shi Yu Yang
Publikováno v:
FEBS Letters. 522:156-160
The physiological function of a recently cloned splice variant of insulin-like growth factor-I (IGF-I; mechano growth factor (MGF)) was studied using an in vitro cell model. Unlike mature IGF-I, the distinct E domain of MGF inhibits terminal differen
Publikováno v:
FEBS Letters. 441:20-24
A novel peptide technology to produce mimicking peptides of carbohydrate moiety (which we propose to name glyco-replica peptides) is a useful tool to elucidate the functions of glycoconjugate. Carbohydrate moiety of ganglioside GD1alpha functions as