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Autor:
Maike Streckert, Axel M. Gressner, Linda Bonzel, Marcin Stopa, Bert Delvoux, S Dooley, Peter ten Dijke
Publikováno v:
FEBS Letters. 502:4-10
To current knowledge, transforming growth factor beta (TGFbeta) signaling is mandatory to establish liver fibrosis and various molecular interventions designed to affect the TGFbeta system were successfully used to inhibit fibrogenesis. Activated hep
Publikováno v:
FEBS Letters. (1-2):41-45
Tumor necrosis factor (TNF) plays a central role in the state of insulin resistance leading to type II diabetes. We here describe the crosstalk of TNF with insulin signaling cascades in the mouse muscle cell line pmi28. TNF downregulated insulin indu