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Publikováno v:
FEBS Letters. 532:345-350
Adiponectin and resistin, two recently identified adipocyte-specific secretory factors, are able to modulate insulin actions in target tissues. To investigate their expression and hormonal regulation in brown adipocytes, we used the brown adipocyte c
Publikováno v:
Monash University
The objectives of this study were to determine whether leptin synthesis is regulated by the sympathetic nervous system and if so whether beta-adrenergic receptors mediate this effect. We show that sympathetic blockade by reserpine increases leptin mR
Autor:
Josef Houštěk, Ladislav Burýšek
Publikováno v:
FEBS Letters. 411:83-86
Mouse brown adipocytes in primary culture were shown to contain high levels of mRNA for interleukin-1alpha (IL-1alpha) which could be further stimulated up to 9-fold by norepinephrine (NE). Even higher stimulation by NE, up to 40-fold, was found in c
Publikováno v:
FEBS Letters. 334:229-232
At thermoneutral conditions, high steady-state levels of transcripts for both IL-1 alpha and its receptor IL-1RtI were found in specialized thermogenic organ, brown adipose tissue (BAT) of adult mice, as compared with the levels in lymph nodes, brain
Autor:
Françoise Kuehne, Patrizia Arboit, Lorenz Lehr, Patrick Muzzin, Maria Jimenez, Jean-Paul Giacobino, Francis Poulin
Publikováno v:
FEBS letters. 576(1-2)
Knockout of the translation inhibitor 4E-BP1 induces an overexpression of uncoupling protein-1 (UCP1) [Nature Medicine 7 (2001) 1128]. A possible inverse control of UCP1 and 4E-BP1 expressions in mouse brown adipose tissue was investigated. Cold-expo
Autor:
Francesc Villarroya, Teresa Mampel, Marta Giralt, Roser Iglesias, Octavi Viñas, Angel Valmaseda, M C Carmona
Publikováno v:
FEBS letters. 441(3)
The expression of uncoupling protein-2 (UCP2) mRNA is up-regulated during the differentiation of brown adipocytes in primary culture. When differentiation of brown adipocytes is impaired, UCP2 mRNA expression is down-regulated. 9-cis Retinoic acid ca
Publikováno v:
FEBS Letters. (25):5680-5684
To examine whether cold-induced vascular endothelial growth factor (VEGF) gene expression in brown adipose tissue involved generation of hypoxic oxygen levels by thermogenic processes, we cold-exposed wild-type mice, as well as uncoupling protein-1 (
Autor:
Scott Ribich, Wagner Seixas da-Silva, Mary-Elizabeth Patti, Antonio C. Bianco, Rafael Arrojo e Drigo, Melany Castillo
Publikováno v:
FEBS Letters. (3):539-544
Exposure of cell lines endogenously expressing the thyroid hormone activating enzyme type 2 deiodinase (D2) to the chemical chaperones tauroursodeoxycholic acid (TUDCA) or 4-phenylbutiric acid (4-PBA) increases D2 expression, activity and T3 producti
Autor:
Jean-Paul Giacobino, Kriss Canola, Patrick Muzzin, Françoise Kuehne, Cedric S. Asensio, Lorenz Lehr, Maria Jimenez
Publikováno v:
FEBS Letters. (19):4661-4666
In rodent brown adipose tissue, the beta-adrenergic signaling is believed, by an action on PGC-1alpha, to control UCP1 expression and mitochondriogenesis. We addressed this hypothesis using beta(1)/beta(2)/beta(3)-adrenoceptor knockout (beta-less) br
Autor:
Sandrine Caron, Emmanuel Bouchaert, Folkert Kuipers, Mouaadh Abdelkarim, Jean-Charles Fruchart, Rémy Burcelin, Bart Staels, Bertrand Cariou, Julie Dumont
Publikováno v:
FEBS Letters
FEBS Letters, 2007, 581 (27), pp.5191-8. ⟨10.1016/j.febslet.2007.09.064⟩
FEBS Letters, 581(27), 5191-5198. Wiley
FEBS Letters, Wiley, 2007, 581 (27), pp.5191-8. ⟨10.1016/j.febslet.2007.09.064⟩
FEBS Letters, 2007, 581 (27), pp.5191-8. ⟨10.1016/j.febslet.2007.09.064⟩
FEBS Letters, 581(27), 5191-5198. Wiley
FEBS Letters, Wiley, 2007, 581 (27), pp.5191-8. ⟨10.1016/j.febslet.2007.09.064⟩
The role of the nuclear receptor FXR in adaptive thermogenesis was investigated using FXR-deficient mice. Despite elevated serum bile acid concentrations and increased mRNA expression profiles of thermogenic genes in brown adipose tissue, FXR-deficie