Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jiang A"'
Autor:
Lei Su, Jiang Huai Wang, Zhifeng Liu, Yawei Liu, Juan Wang, Jia Xu, Yong Jiang, Jinghua Liu, Xuegang Sun
Publikováno v:
FEBS Journal. 281:2202-2213
Inducible nitric oxide synthase (iNOS) plays a central role in tissue damage during endotoxic shock. However, the underlying mechanisms that control transcription of iNOS are not completely defined. A screening strategy with DNA pull-down technology
Autor:
Xiaolong Wang, Haiquan Qiao, Xueying Sun, Hongchi Jiang, Lele Lin, Xian Jiang, Bo Sun, Xuesong Dong, Zheng Wei, Bo Zhai, Geoffrey W. Krissansen, Xue-Pu Sun, Qiang Zhang
Publikováno v:
FEBS Journal. 281:115-128
This study investigated the contribution of survivin and its upstream regulators, AKT and hypoxia-inducible factor 1α (HIF-1α), to the resistance of gastric cancer cells to cisplatin (CDDP). We found that over-expression of survivin increased the r
Publikováno v:
FEBS Journal. 282:3799-3807
Acute kidney injury (AKI), which is associated with high mortality rates, involves renal inflammation related to the activation of innate immunity. The inflammatory response in AKI involves the inflammasome, which integrates danger signals into caspa
Autor:
Jinping Lin, Shuiqin Jiang, Zhiqiang Yao, Lujia Zhang, Dongzhi Wei, Dongbing Cui, Bei Gao, Y. Adam Yuan
Publikováno v:
FEBS Journal. 282:2339-2351
Coenzyme engineering, especially for altered coenzyme specificity, has been a research hotspot for more than a decade. In the present study, a novel computational strategy that enhances the hydrogen-bond interaction between an enzyme and a coenzyme w
Publikováno v:
FEBS Journal. 281:4718-4730
Dysregulation of microRNA is strongly implicated in the chemoresistance of cancer. In this study, we found that miR-149 was downregulated and involved in chemoresistance in adriamycin (ADM)-resistant human breast cancer cells (MCF-7/ADM). Downregulat
Autor:
Xiao Chun Huang, Rong Mei Liang, Yong Bing Cao, Jun Chen, Xi Chen, Yong Hong Tan, Yun Ping Jiang, Ting Ting Hu, Zhao Hui Dong, Nan Li, Yuan Ying Jiang, Bao Di Dai, Shi Hua Wang, Xiao Lan Yong
Publikováno v:
FEBS Journal. 278:1075-1085
Candida infections have become an increasingly significant problem, mainly because of the widespread nature of Candida and drug resistance. There is an urgent need to develop new classes of drugs for the treatment of opportunistic Candida infections,
Autor:
Deng-Yu Chen, Jiang Huai Wang, Xiaowei Gong, Peng Deng, Yong Jiang, Shan-Chao Zhao, Yawei Liu, Jinghua Liu, Ming-zhe Zhao, Zhi-jie Li, Yu-sheng Li, Jing Tang, Tianyu Zhong
Publikováno v:
FEBS Journal. 276:4598-4606
It has been well documented that both endogenous inflammatory mediator advanced glycation end products (AGEs) and exogenous inflammatory inducer lipopolysaccharide play key roles in the initiation and development of inflammatory diseases. However, th
Autor:
Yuanheng Cai, Sheng Yang, Peter Trodler, Yan Wu, Shimin Jiang, Yinhua Lu, Weihong Jiang, Weiwen Zhang
Publikováno v:
FEBS Journal. 276:3575-3588
Hydantoinases (HYDs) are important enzymes for industrial production of optically pure amino acids, which are widely used as precursors for various semi-synthetic antibiotics. By a process coupling genomic data mining with activity screening, a new h
Autor:
Wen-Quan Liu, Ran Li, Xiao-yan Xie, Lei Jiang, Wen-li Yang, Xuejiao Shi, Qiang Zhu, Jun-Zhe Zhang, Qiuying Liu, Yang Qin, Bo Yang, Wenyan Shen, Ya-Jun Ge, Xiaoqin Yu, Bo Li, Ling Wei
Publikováno v:
FEBS Journal. 281:2713-2725
CCCTC-binding factor (CTCF), a highly conserved zinc finger protein, is a master organizer of genome spatial organization and has multiple functions in gene regulation. Mounting evidence indicates that CTCF regulates the imprinted genes Igf2 and H19
Autor:
Dunquan Jiang, Hao Zhou, Jin Jin, Zihe Rao, Weihong Zhou, Qianqian Zheng, Mark Bartlam, Qingqing Zhang
Publikováno v:
FEBS Journal. 281:331-341
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the most devastating human diseases, and is responsible for ~ 2 million deaths worldwide each year. The nutritional requirements for the growth of mycobacteria have been extensively s