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pro vyhledávání: '"Marios C Papadopoulos"'
Autor:
Zsolt Zador, Marios C. Papadopoulos, Geoffrey T. Manley, Alan S. Verkman, Songwan Jin, Mazin Magzoub
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 22(3)
Diffusion in brain extracellular space (ECS) is important for nonsynaptic intercellular communication, extracellular ionic buffering, and delivery of drugs and metabolites. We measured macromolecular diffusion in normally light-inaccessible regions o
Autor:
Marios C. Papadopoulos, Songwan Jin, Kurtis I. Auguste, Kazunori Uchida, Alan S. Verkman, Donghong Yan, Geoffrey T. Manley
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 21(1)
We reported previously that astroglia cultured from aquaporin-4-deficient (AQP4-/-) mice migrate more slowly in vitro than those from wild-type (AQP4+/+) mice (J. Cell Sci. 2005;118, 5691-5698). Here, we investigate the migration of fluorescently lab
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 18(11)
Aquaporin-4 (AQP4) is the major water channel in the brain, expressed predominantly in astroglial cell membranes. Initial studies in AQP4-deficient mice showed reduced cellular brain edema following water intoxication and ischemic stroke. We hypothes