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Transcutaneous immunization with heat-labile enterotoxin: development of a needle-free vaccine patch
Autor:
Larry Ellingsworth, Gregory M. Glenn, Jianmei Yu, David Flyer, David Frerichs, Sarah A. Frech, Robert C. Seid
Publikováno v:
Expert review of vaccines. 6(5)
The skin is an attractive target for vaccine delivery. Adjuvants and antigens delivered into the skin can result in potent immune responses and an unmatched safety profile. The heat-labile enterotoxin (LT) from Escherichia coli, which acts both as an