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Publikováno v:
Expert Review of Hematology. 10:853-862
The management of Acute Myeloid Leukemia (AML) (with the exception of acute promyelocytic leukemia) has remained largely unchanged over the past 40 years. In particular, patients defined as high-risk, according to the 2017 European Leukemia Net recom
Autor:
Melissa Alsina, Jae Hoon Lee, Paul G. Richardson, Vania Hungria, Hermann Einsele, Philippe Moreau, Jacob P. Laubach, Sagar Lonial, Jian Hou, Jesús F. San-Miguel
Publikováno v:
Expert Review of Hematology. 10:229-237
A significant unmet need exists in patients with relapsed or refractory multiple myeloma (MM), which remains an incurable disease despite recent advances in the field. One such development was the use of deacetylase inhibitors (DACi), which exert uni
Autor:
Jonathan Canaani, Arnon Nagler
Publikováno v:
Expert Review of Hematology. 9:997-1005
Therapy for the myelodysplastic syndromes (MDS) is an evolving area of research which has made significant use of the increased understanding of the complex biology of these disorders. Novel agents targeting multiple pathogenic pathways are being act