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Publikováno v:
Expert Opinion on Therapeutic Targets. 22:783-797
Introduction: Triggering of the glucocorticoid-induced TNFR-related gene (GITR) increases the activation of T lymphocytes and other immune system cells; furthermore, its ligand, GITRL, delivers signals in the cells where it is expressed.Areas covered
Autor:
Kristopher T. Kahle, Eric Delpire
Publikováno v:
Expert Opinion on Therapeutic Targets. 21:113-116
The SLC12A family of K-Cl cotransporters mediates the tightly coupled and electroneutral movement of K+ and Cl- across plasma membranes. In the brain and spinal cord, KCC2 (SLC12A5) plays a key rol...