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Autor:
Robert D. Hyldahl, Jayson R. Gifford, Lance E. Davidson, Chad R. Hancock, Paul S. Hafen, Allen C. Parcell, Gary W. Mack
Publikováno v:
Experimental Physiology, Vol 109, Iss 2, Pp 165-174 (2024)
Abstract The Tour Divide (TD) is a 4385 km ultra‐endurance bicycle race that follows the continental divide from Canada to Mexico. In this case study, we performed a comprehensive molecular and physiological profile before and after the completion
Externí odkaz:
https://doaj.org/article/0e26490f416c437ba963d772c9064514
Autor:
Jack S. Talbot, Dean R. Perkins, Christine M. Tallon, Tony G. Dawkins, Andrew J. M. Douglas, Ryan Beckerleg, Andrew Crofts, Melissa E. Wright, Saajan Davies, Jessica J. Steventon, Kevin Murphy, Rachel N. Lord, Christopher J. A. Pugh, Jon L. Oliver, Rhodri S. Lloyd, Philip N. Ainslie, Ali M. McManus, Mike Stembridge
Publikováno v:
Experimental Physiology, Vol 108, Iss 12, Pp 1500-1515 (2023)
Abstract Global cerebral blood flow (gCBF) and cerebrovascular reactivity to hypercapnia (CVRCO2) are modulated by gonadal hormone activity, while insulin‐like growth factor 1 facilitates exercise‐mediated cerebral angiogenesis in adults. Whether
Externí odkaz:
https://doaj.org/article/20b61a3e79984408bcdf31f2b7030741
Autor:
Adam T. Corkery, Kathleen B. Miller, Carissa A. Loeper, Laura H. Tetri, Andrew G. Pearson, Nicole A. Loggie, Anna J. Howery, Marlowe W. Eldridge, Jill N. Barnes
Publikováno v:
Experimental Physiology, Vol 108, Iss 8, Pp 1047-1056 (2023)
Abstract Platelet activation may contribute to age‐related cerebrovascular dysfunction by interacting with the endothelial cells that regulate the response to vasodilatory stimuli. This study evaluated the relationship between a platelet inhibitor,
Externí odkaz:
https://doaj.org/article/5887b7b744904931943c0d84424b7578
Publikováno v:
Experimental Physiology. 102:1158-1176
Critical power (CP) is a fundamental parameter defining high-intensity exercise tolerance and is related to the time constant of phase II pulmonary oxygen uptake kinetics (τVO2). To test the hypothesis that this relationship is causal we determined
Autor:
Manabu Shibasaki, Shigehiko Ogoh, Tadayoshi Miyamoto, Kazunobu Okazaki, Kohei Sato, Ai Hirasawa, Tomoko Sadamoto
Publikováno v:
Experimental Physiology. 100:259-266
New Findings What is the central question of this study? Recently, the heterogeneity of the cerebral arterial circulation has been argued. Orthostatic tolerance may be associated with an orthostatic stress-induced change in blood flow in vertebral ar
Publikováno v:
Experimental Physiology. 99:937-950
The presympathetic neurons in the rostral ventrolateral medulla (RVLM) are considered to be the source of the sympathetic activity, and there is experimental evidence that these cells present intrinsic autodepolarization. There is also evidence that
Autor:
R. Dirk Noyes, J. David Symons, John McDaniel, Markus Amann, D. Walter Wray, Robert H.I. Andtbacka, Russell S. Richardson, Melissa A. H. Witman, Stephen J. Ives
Publikováno v:
Experimental Physiology. 96:907-918
Heat and cold exposure can decrease and increase total peripheral resistance, respectively, in humans. With unique access to human skeletal muscle feed arteries, we sought both to characterize these vessels and to determine the interaction between te
Publikováno v:
Experimental Physiology. 88:527-531
Previous studies have shown that prolactin administration to pregnant rats results in offspring with enhanced abundance of the brown adipose tissue-specific uncoupling protein (UCP) 1. The present study therefore aimed to determine whether a similar
Autor:
Ching-Sui Hung, Wen-Chieh Liao, Hsin-Hua Li, Chiung-Hui Liu, Wei-Han Wang, Chih-Li Lin, Wen-Yuan Liu, Pin-Jiun Lin, Ying-Jui Ho, Li-Ho Tseng, Hsin Tung
Publikováno v:
Experimental Physiology. 106:1814-1828
NEW FINDINGS What is the central question of this study? Imbalance of activities between GABAergic and glutamatergic systems is involved in epilepsy. It is not known whether simultaneously increasing GABAergic and decreasing glutamatergic activity us