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Autor:
Hatam GholamReza, Namdar Ahmadabad Hasan, Shafiei Reza, Amirali Ghahremani, Ghatee Mohammad Amin, BakhshiJoibari Fahimeh, Nezafat Firizi Maryam
Publikováno v:
Experimental Parasitology. 203:1-7
Fucose-mannose ligand (FML) is a soluble antigen purified from Leishmania donovani complex and used for diagnosis, prognosis, and vaccine development against visceral leishmaniasis (VL). We aimed to explore the effects of FML on the production of cyt
Autor:
Björn Andersson, Milene Höehr de Moraes, Glauber Wagner, Carime Lessa Mansur Pontes, Patrícia Hermes Stoco, Edmundo C. Grisard, Débora Denardin Lückemeyer
Publikováno v:
Experimental parasitology. 230
Trypanosoma rangeli is a non-virulent hemoflagellate parasite infecting humans, wild and domestic mammals in Central and Latin America. The share of genotypic, phenotypic, and biological similarities with the virulent, human-infective T. cruzi and T.
Autor:
Wagner Faria Messias, Nayara Braga Emidio, Elaine Soares Coimbra, Michelle de Lima Detoni, Leonardo Ramos Quellis, Gabriane Nascimento Porcino, Danielle Gomes Marconato, Priscila V. S. Z. Capriles, Marcos José Marques, Priscila Faria-Pinto, Ana Carolina Ribeiro Gomes Maia, Laura Lavorato Soldati, Eveline Gomes Vasconcelos
Publikováno v:
Experimental Parasitology. 200:1-6
Nucleoside triphosphate diphosphohydrolase (NTPDase) 1 from intracellular amastigotes of Leishmania infantum-infected macrophage was identified by immunocytochemistry and confocal laser scanning microscopy using antibodies that specifically recognize
Publikováno v:
Experimental Parasitology. 199:1-8
Schistosomiasis remains a severe problem of public health in developing countries. The development of resistance to praziquantel (PZQ) has justified the search for new alternative chemotherapies with new formulations, more effective, and without adve
Autor:
Elaine Soares Coimbra, Vinicio T.S. Coelho, Patrícia A.F. Ribeiro, Guilherme R. Pereira, Guilherme Firmo De Matos, Luísa Perin, Pedro Henrique De Almeida Simões Neves, Eduardo A.F. Coelho, Grasiele S.V. Tavares, Andreza Cristina Gomes Ferreira, Daniel Dias, Débora V.C. Mendonça, Fernanda Ludolf, Daniela P. Lage, Luciana M.R. Antinarelli, Tauane G. Soyer, Miguel A. Chávez-Fumagalli
Publikováno v:
Experimental Parasitology. 199:30-37
The treatment against leishmaniasis presents problems, since the currently used drugs are toxic and/or have high costs. In addition, parasite resistance has increased. As a consequence, in this study, a chloroquinolin derivative, namely 7-chloro-N,N-
Autor:
Elżbieta Wandurska-Nowak, Paweł P. Jagodziński, Monika Derda, Edward Hadaś, Agnieszka Kolasa-Wołosiuk, Agnieszka Wojtkowiak-Giera, Danuta Kosik-Bogacka
Publikováno v:
Experimental Parasitology. 199:24-29
The genus Acanthamoeba, which may cause different infections in humans, occurs widely in the environment. Lung inflammation caused by these parasites induces pulmonary pathological changes such as pulmonary necrosis, peribronchial plasma cell infiltr
Publikováno v:
Experimental Parasitology. 197:85-92
Chronic hepatic schistosomiasis causes portal hypertension, fibrosis and lethal hepatosplenic complications. Previous studies focused mainly on schistosomicidal drugs and neglected the therapeutic approaches against the vascular complications after p
Autor:
Jie Yu, Peng Zhai, Mingxin Song, Xiaoyun Li, Yang Yu, Ziqun Zhang, Yan Zhang, Shi Meng, Caixia Han
Publikováno v:
Experimental Parasitology. 196:68-72
Helminths and their products can suppress the host immune response and other immunopathologies which may benefit parasite survival. Parasitic nematode Trichinella spiralis (T. spiralis) exert immunomodulatory effect on the host immune response throug
Autor:
Luciana M.R. Antinarelli, Wallace Pacienza Lima, Jacy Gameiro, Priscila V. S. Z. Capriles, Isabela O. Souza, Elaine Soares Coimbra, Adilson David da Silva, Celso Vataru Nakamura, Elizandra Aparecida Britta
Publikováno v:
Experimental Parasitology. 195:78-86
Currently, available treatment options for leishmaniasis are limited and unsatisfactory. In a previous study, a quinoline derivative (AMQ-j), exhibited a strong effect against Leishmania amazonensis and its antileishmanial activity was preliminarily
Autor:
Haining Shi, Xue Bai, Bin Tang, Libo Wang, Mingyuan Liu, He Gao, Xiu-Ping Wu, Wang Xuelin, Xiaolei Liu
Publikováno v:
Experimental Parasitology. 195:8-18
Serine proteases have been identified as important molecules that are involved in many parasitic infections, and these molecules have also been suggested to play important roles in Trichinella spiralis infections. In the present study, the antigenic