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Autor:
Björn Andersson, Milene Höehr de Moraes, Glauber Wagner, Carime Lessa Mansur Pontes, Patrícia Hermes Stoco, Edmundo C. Grisard, Débora Denardin Lückemeyer
Publikováno v:
Experimental parasitology. 230
Trypanosoma rangeli is a non-virulent hemoflagellate parasite infecting humans, wild and domestic mammals in Central and Latin America. The share of genotypic, phenotypic, and biological similarities with the virulent, human-infective T. cruzi and T.
Autor:
Hatam GholamReza, Namdar Ahmadabad Hasan, Shafiei Reza, Amirali Ghahremani, Ghatee Mohammad Amin, BakhshiJoibari Fahimeh, Nezafat Firizi Maryam
Publikováno v:
Experimental Parasitology. 203:1-7
Fucose-mannose ligand (FML) is a soluble antigen purified from Leishmania donovani complex and used for diagnosis, prognosis, and vaccine development against visceral leishmaniasis (VL). We aimed to explore the effects of FML on the production of cyt
Publikováno v:
Experimental Parasitology. 199:1-8
Schistosomiasis remains a severe problem of public health in developing countries. The development of resistance to praziquantel (PZQ) has justified the search for new alternative chemotherapies with new formulations, more effective, and without adve
Autor:
Elaine Soares Coimbra, Vinicio T.S. Coelho, Patrícia A.F. Ribeiro, Guilherme R. Pereira, Guilherme Firmo De Matos, Luísa Perin, Pedro Henrique De Almeida Simões Neves, Eduardo A.F. Coelho, Grasiele S.V. Tavares, Andreza Cristina Gomes Ferreira, Daniel Dias, Débora V.C. Mendonça, Fernanda Ludolf, Daniela P. Lage, Luciana M.R. Antinarelli, Tauane G. Soyer, Miguel A. Chávez-Fumagalli
Publikováno v:
Experimental Parasitology. 199:30-37
The treatment against leishmaniasis presents problems, since the currently used drugs are toxic and/or have high costs. In addition, parasite resistance has increased. As a consequence, in this study, a chloroquinolin derivative, namely 7-chloro-N,N-
Publikováno v:
Experimental Parasitology. 197:85-92
Chronic hepatic schistosomiasis causes portal hypertension, fibrosis and lethal hepatosplenic complications. Previous studies focused mainly on schistosomicidal drugs and neglected the therapeutic approaches against the vascular complications after p
Autor:
Luciana M.R. Antinarelli, Wallace Pacienza Lima, Jacy Gameiro, Priscila V. S. Z. Capriles, Isabela O. Souza, Elaine Soares Coimbra, Adilson David da Silva, Celso Vataru Nakamura, Elizandra Aparecida Britta
Publikováno v:
Experimental Parasitology. 195:78-86
Currently, available treatment options for leishmaniasis are limited and unsatisfactory. In a previous study, a quinoline derivative (AMQ-j), exhibited a strong effect against Leishmania amazonensis and its antileishmanial activity was preliminarily
Autor:
Karolina Kot, Natalia Łanocha-Arendarczyk, Danuta Kosik-Bogacka, Izabela Gutowska, Irena Baranowska-Bosiacka, Emilia Metryka
Publikováno v:
Experimental Parasitology. 193:58-65
The role of oxidative stress in the pathogenicity of acanthamoebiasis is an important aspect of the intricate and complex host–parasite relationship. The aim of this experimental study was to determine oxidative stress through the assessment of lip
Autor:
Bahareh Mirzaalizadeh, Ahmad Daryani, Mahbobeh Montazeri, Mohammad Ali Ebrahimzadeh, Mohammad Taghi Rahimi, Shahabeddin Sarvi, Saeed Mehrzadi, Zahra Mirabediny, Monireh Golpour, Mehryar Zargari, Mehdi Sharif
Publikováno v:
Experimental Parasitology. 192:6-11
Toxoplasmosis is a worldwide disease caused by the protozoan parasite Toxoplasma gondii (T. gondii), which is most commonly treated by pyrimethamine and sulfadiazine. However, this treatment presents several adverse side effects; Thus, new drugs with
Publikováno v:
Experimental Parasitology. 192:93-97
Microsporidia are a group of obligate intracellular eukaryotic parasites, which are able to infect a wide range of animals, including humans. Four genotypes of Encephalitozoon cuniculi have been found to date. The different courses of microsporidiosi
Autor:
Annahita Rezaie, Masoud Ghorbanpoor, Somayeh Bahrami, Mohammad Reza Tabandeh, Mohammad Razi Jalali, Moslem Safari
Publikováno v:
Experimental parasitology. 222
Leishmaniasis is one of the most neglected tropical infectious diseases in the world. The emergence of drug resistance and toxicity and the high cost of the available drugs with a lack of new anti-leishmanial drugs highlight the need to search for ne