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Autor:
Wagner Faria Messias, Nayara Braga Emidio, Elaine Soares Coimbra, Michelle de Lima Detoni, Leonardo Ramos Quellis, Gabriane Nascimento Porcino, Danielle Gomes Marconato, Priscila V. S. Z. Capriles, Marcos José Marques, Priscila Faria-Pinto, Ana Carolina Ribeiro Gomes Maia, Laura Lavorato Soldati, Eveline Gomes Vasconcelos
Publikováno v:
Experimental Parasitology. 200:1-6
Nucleoside triphosphate diphosphohydrolase (NTPDase) 1 from intracellular amastigotes of Leishmania infantum-infected macrophage was identified by immunocytochemistry and confocal laser scanning microscopy using antibodies that specifically recognize
Publikováno v:
Experimental Parasitology. 199:1-8
Schistosomiasis remains a severe problem of public health in developing countries. The development of resistance to praziquantel (PZQ) has justified the search for new alternative chemotherapies with new formulations, more effective, and without adve
Publikováno v:
Experimental Parasitology. 197:85-92
Chronic hepatic schistosomiasis causes portal hypertension, fibrosis and lethal hepatosplenic complications. Previous studies focused mainly on schistosomicidal drugs and neglected the therapeutic approaches against the vascular complications after p
Autor:
Karolina Kot, Natalia Łanocha-Arendarczyk, Danuta Kosik-Bogacka, Izabela Gutowska, Irena Baranowska-Bosiacka, Emilia Metryka
Publikováno v:
Experimental Parasitology. 193:58-65
The role of oxidative stress in the pathogenicity of acanthamoebiasis is an important aspect of the intricate and complex host–parasite relationship. The aim of this experimental study was to determine oxidative stress through the assessment of lip
Autor:
Patricia Andrea Garavaglia, Gabriela Andrea Garcia, Joaquin Juan Bautista Cannata, Cristina Graciela Maidana, Juan Matías Viecenz, Laura Mónica Tasso
Publikováno v:
Experimental parasitology. 231
Dihydroxyacetone (DHA) can be used as an energy source by many cell types; however, it is toxic at high concentrations. The enzyme dihydroxyacetone kinase (DAK) has shown to be involved in DHA detoxification and osmoregulation. Among protozoa of the
Publikováno v:
Exp Parasitol
The parasitic protozoan Leishmania infantum resides primarily in macrophages throughout mammalian infection. Infection is initiated by deposition of the metacyclic promastigote into the dermis of a mammalian host by the sand fly vector. Promastigotes
Autor:
Gabriel Antonio Nogueira Nascentes, Karen A Norris, Gustavo Caetano Silva, Luis Eduardo Ramirez, Wendell Sérgio Ferreira Meira, Tatiane Marques, Priscila Moraes Henrique Paiva
Publikováno v:
Experimental Parasitology. 184:103-108
Experimental Chagas disease has been used as a model to identify several host/parasite interaction factors involved in immune responses to Trypanosoma cruzi infection. One of the factors inherent to this parasite is the complement regulatory protein
Publikováno v:
Experimental Parasitology. 178:51-59
Schistosomiasis is the second most common human parasitic disease worldwide. It is responsible for 300000 deaths per year. Liver fibrosis is the main pathology of schistosomiasis and its complications are the major cause of death in infected cases. U
Autor:
Dionatas Ulisses de Oliveira Meneguetti, Neuza Biguinati de Barros, Roberto Nicolete, Sharon Rose Aragão Macedo, Amália dos Santos Ferreira, Thamy Yamashita Shibayama, Valdir Alves Facundo
Publikováno v:
Experimental parasitology. 205
Leishmaniases, caused by Leishmania spp., are among the most prevalent infectious diseases in the world and their treatment may present high toxicity and side/adverse effects. This study evaluated the antileishmanial activity of the Hexanic Eluate su
Autor:
Ge Ge Sun, Shao Rong Long, Zhong Quan Wang, Peng Jiang, Kai Xia Guo, Jun Jun Lei, Yao Zhang, Jing Cui, Hua Nan Ren, Ruo Dan Liu
Publikováno v:
Experimental parasitology. 201
The aim of this study was to observe the intestinal mucosal/systemic responses triggered by intranasal vaccination using recombinant Trichinella spiralis serine protease (rTsSP) and its capacity to elicit immune protection against larva challenge in