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Publikováno v:
Experimental Parasitology. 199:1-8
Schistosomiasis remains a severe problem of public health in developing countries. The development of resistance to praziquantel (PZQ) has justified the search for new alternative chemotherapies with new formulations, more effective, and without adve
Autor:
Luciana M.R. Antinarelli, Wallace Pacienza Lima, Jacy Gameiro, Priscila V. S. Z. Capriles, Isabela O. Souza, Elaine Soares Coimbra, Adilson David da Silva, Celso Vataru Nakamura, Elizandra Aparecida Britta
Publikováno v:
Experimental Parasitology. 195:78-86
Currently, available treatment options for leishmaniasis are limited and unsatisfactory. In a previous study, a quinoline derivative (AMQ-j), exhibited a strong effect against Leishmania amazonensis and its antileishmanial activity was preliminarily
Autor:
Bruno Polack, Christine Julien, Aurélie Chevillot, Karim Tarik Adjou, Eric Auclair, Myriam Thomas, Mohamed Mammeri, Jean-Philippe Marden, Isabelle Vallée
Publikováno v:
Experimental Parasitology
6th International Giardia and Cryptosporidium Conference (IGCC)
6th International Giardia and Cryptosporidium Conference (IGCC), Apr 2017, Havana, Cuba. pp.8, ⟨10.1016/j.exppara.2018.09.003⟩
6th International Giardia and Cryptosporidium Conference (IGCC)
6th International Giardia and Cryptosporidium Conference (IGCC), Apr 2017, Havana, Cuba. pp.8, ⟨10.1016/j.exppara.2018.09.003⟩
International audience; Cryptosporidiosis is a zoonotic disease caused by species in the genus Cryptosporidium. In young ruminants, Cryptosporidium parvum causes economically significant disease with mild to severe clinical signs and occasional death
Autor:
Karolina Kot, Natalia Łanocha-Arendarczyk, Danuta Kosik-Bogacka, Izabela Gutowska, Irena Baranowska-Bosiacka, Emilia Metryka
Publikováno v:
Experimental Parasitology. 193:58-65
The role of oxidative stress in the pathogenicity of acanthamoebiasis is an important aspect of the intricate and complex host–parasite relationship. The aim of this experimental study was to determine oxidative stress through the assessment of lip
Autor:
Bahareh Mirzaalizadeh, Ahmad Daryani, Mahbobeh Montazeri, Mohammad Ali Ebrahimzadeh, Mohammad Taghi Rahimi, Shahabeddin Sarvi, Saeed Mehrzadi, Zahra Mirabediny, Monireh Golpour, Mehryar Zargari, Mehdi Sharif
Publikováno v:
Experimental Parasitology. 192:6-11
Toxoplasmosis is a worldwide disease caused by the protozoan parasite Toxoplasma gondii (T. gondii), which is most commonly treated by pyrimethamine and sulfadiazine. However, this treatment presents several adverse side effects; Thus, new drugs with
Publikováno v:
Experimental Parasitology. 192:25-35
Perkinsus protozoan parasites have been associated with high mortality of bivalves worldwide, including Brazil. The use of antiproliferative drugs to treat the Perkinsosis is an unusual prophylactic strategy. However, because of their environment imp
Autor:
Marián Várady, Johan Höglund, Michaela Komáromyová, Georg von Samson-Himmelstjerna, Paulius Baltrušis
Publikováno v:
Experimental parasitology. 217
The ruminant livestock production sector is under threat due to the infections with gastrointestinal nematode parasites and the subsequent development of anthelmintic resistance. One of most common and pathogenic species in small ruminants is Haemonc
Autor:
Rishila Ghosh, Nivedita Roy, Subrata Majumdar, Sweta Ghosh, Subir Kumar Juin, Suchandra Bhattacharya Majumdar
Publikováno v:
Experimental parasitology. 217
Immunomodulation is an emerging concept to combat infection in recent years. Immunomodulators like arabinosylated-lipoarabinomannan (Ara-LAM) and glycyrrhizic-acid (GA) possess anti-leishmanial property, whereas sodium-antimony-gluconate (SAG) is sti
Publikováno v:
Experimental parasitology. 216
Toxoplasma gondii is an important pathogen that causes serious public health problems. Currently, therapeutic drugs for toxoplasmosis cause serious side effects, and more effective and novel substances with relatively low toxicity are urgently needed
Autor:
Gustavo F. Da Silva, Julio Cesar Moraes, Luiz Claudio Miletti, Maria de Lourdes Borba Magalhães, Lina Maria Salazar Echeverri
Publikováno v:
Experimental parasitology. 212
A phage-display library was generated using a Bus thalamus scorpion toxin (BTK-2) as a peptide scaffold. BTK-2 belongs to the disulfide-rich family of proteins with pronounced structural stability due to the presence of three disulfide bridges that c