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Autor:
Elaine Soares Coimbra, Vinicio T.S. Coelho, Patrícia A.F. Ribeiro, Guilherme R. Pereira, Guilherme Firmo De Matos, Luísa Perin, Pedro Henrique De Almeida Simões Neves, Eduardo A.F. Coelho, Grasiele S.V. Tavares, Andreza Cristina Gomes Ferreira, Daniel Dias, Débora V.C. Mendonça, Fernanda Ludolf, Daniela P. Lage, Luciana M.R. Antinarelli, Tauane G. Soyer, Miguel A. Chávez-Fumagalli
Publikováno v:
Experimental Parasitology. 199:30-37
The treatment against leishmaniasis presents problems, since the currently used drugs are toxic and/or have high costs. In addition, parasite resistance has increased. As a consequence, in this study, a chloroquinolin derivative, namely 7-chloro-N,N-
Autor:
Luciana M.R. Antinarelli, Wallace Pacienza Lima, Jacy Gameiro, Priscila V. S. Z. Capriles, Isabela O. Souza, Elaine Soares Coimbra, Adilson David da Silva, Celso Vataru Nakamura, Elizandra Aparecida Britta
Publikováno v:
Experimental Parasitology. 195:78-86
Currently, available treatment options for leishmaniasis are limited and unsatisfactory. In a previous study, a quinoline derivative (AMQ-j), exhibited a strong effect against Leishmania amazonensis and its antileishmanial activity was preliminarily
Autor:
Bruno Polack, Christine Julien, Aurélie Chevillot, Karim Tarik Adjou, Eric Auclair, Myriam Thomas, Mohamed Mammeri, Jean-Philippe Marden, Isabelle Vallée
Publikováno v:
Experimental Parasitology
6th International Giardia and Cryptosporidium Conference (IGCC)
6th International Giardia and Cryptosporidium Conference (IGCC), Apr 2017, Havana, Cuba. pp.8, ⟨10.1016/j.exppara.2018.09.003⟩
6th International Giardia and Cryptosporidium Conference (IGCC)
6th International Giardia and Cryptosporidium Conference (IGCC), Apr 2017, Havana, Cuba. pp.8, ⟨10.1016/j.exppara.2018.09.003⟩
International audience; Cryptosporidiosis is a zoonotic disease caused by species in the genus Cryptosporidium. In young ruminants, Cryptosporidium parvum causes economically significant disease with mild to severe clinical signs and occasional death
Publikováno v:
Experimental Parasitology. 192:25-35
Perkinsus protozoan parasites have been associated with high mortality of bivalves worldwide, including Brazil. The use of antiproliferative drugs to treat the Perkinsosis is an unusual prophylactic strategy. However, because of their environment imp
Autor:
Alessandra M. Silva, Débora V.C. Mendonça, Luciana M.R. Antinarelli, Elaine Soares Coimbra, João A. Oliveira-da-Silva, Camila S. Freitas, Maria Victoria Humbert, Bruno Mendes Roatt, Eduardo A.F. Coelho, Rory Cristiane Fortes de Brito, Vívian T. Martins, Miguel A. Chávez-Fumagalli, Fernanda F. Ramos, Daniela P. Lage, Grasiele S.V. Tavares, Fernanda Ludolf, Thiago A.R. Reis, Rafaella R Costa, Amanda S. Machado
Publikováno v:
Experimental parasitology. 221
Treatment for visceral leishmaniasis (VL) is hindered mainly by the toxicity and/or high cost of therapeutic drugs. In addition, parasite resistance has been registered. Thus, there is an urgent need for the identification of novel, effective and low
Autor:
Cristiano C. Bandeira, Bruno G. de Faria, Marina L.R. Alves, Juliana Martins Ribeiro, Vanessa Peruhype-Magalhães, Jude E. Uzonna, Francisco Oliveira Vieira, Elaine M. Souza-Fagundes, Rodolfo Cordeiro Giunchetti, Andréa Teixeira-Carvalho
Publikováno v:
Experimental parasitology. 216
Therapeutic options for the treatment of leishmaniasis are insufficient and need improvements owing to their low efficiency and high toxicity as well as the emergence of resistant strains. The limited number of new drugs for neglected diseases and la
Autor:
Rishila Ghosh, Nivedita Roy, Subrata Majumdar, Sweta Ghosh, Subir Kumar Juin, Suchandra Bhattacharya Majumdar
Publikováno v:
Experimental parasitology. 217
Immunomodulation is an emerging concept to combat infection in recent years. Immunomodulators like arabinosylated-lipoarabinomannan (Ara-LAM) and glycyrrhizic-acid (GA) possess anti-leishmanial property, whereas sodium-antimony-gluconate (SAG) is sti
Autor:
Subhash Chander, Rosa M. Reguera, Murugesan Sankaranarayanan, Rafael Balaña-Fouce, M. Yolanda Pérez-Pertejo, Ruben Carbajo-Andres, Penta Ashok, Kondapalli Venkata Gowri Chandra Sekhar
Publikováno v:
Experimental Parasitology. 189:49-60
In the present study, anti-leishmanial evaluation of twenty four structurally diverse compounds based on benzopiperidine, benzopyridine and phenylpiperazine nucleuses against Leishmania infantum has been reported. Cytotoxicity studies of all the comp
Autor:
Xuenan Xuan, Huanping Guo, Seung-Hun Lee, Yang Gao, Mohamed Abdo Rizk, Naoaki Yokoyama, Byamukama Benedicto, Maria Agnes Tumwebaze, Eloiza May Galon, Paul Franck Adjou Moumouni, Mingming Liu, Yongchang Li, Amani Magdy Beshbishy, Arifin Budiman Nugraha, Ikuo Igarashi, Shengwei Ji, Jixu Li
Publikováno v:
Experimental parasitology. 210
Babesia (B.) bovis is one of the main etiological agents of bovine babesiosis, causes serious economic losses to the cattle industry. Control of bovine babesiosis has been hindered by the limited treatment selection for B. bovis, thus, new options ar
Autor:
Wisnu Nurcahyo, Dana Květoňová, Radka Pecková, Bohumil Sak, Karel Doležal, Ivona Foitová, Martin Kváč
Publikováno v:
Experimental Parasitology. 184:39-45
Piper betle has been used as a medicinal plant in traditional medical systems throughout South and South East Asia. Experimental studies have revealed its wide and diverse biological and pharmacological effects. In this study, antigiardial activity o