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Autor:
Matteo M. Althoen, Edward P. Washabaugh, Rajiv Ranganathan, Chandramouli Krishnan, Courtney E. Reid
Publikováno v:
Experimental Gerontology. 111:45-52
Evidence from upper-extremity literature suggests that the normal ageing process affects an individual’s ability to learn and retain a motor skill, but spares their ability to transfer the skill to the untrained, opposite limb. While this phenomeno
Autor:
Hassan Mohamed Elsangedy, Geovani Araújo Dantas Macêdo, Andrés Vivas, Eduardo Caldas Costa, Rodrigo Alberto Vieira Browne, Ludmila Lucena Pereira Cabral, Eduardo Bodnariuc Fontes, Gledson Tavares Amorim Oliveira
Publikováno v:
Experimental Gerontology
Background This study reports the accelerometer-based physical activity (PA) and sedentary behavior (SB) before and during the COVID-19 pandemic in hypertensive older adults. Methods Thirty-five hypertensive older adults were included in this observa
Publikováno v:
Experimental Gerontology
Background Understanding the root cause of the age-related impairment in muscle adaptive remodelling with resistance exercise training (RET) and developing pragmatic and accessible resistance exercise for older adults, are essential research directiv
Publikováno v:
Experimental Gerontology
Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure. The mechanisms driving age-related tissue fibrosis and cardiac dysfun
Publikováno v:
Sibille, K T, Mcbeth, J, Smith, D & Wilkie, R 2017, ' Allostatic load and pain severity in older adults : Results from the English Longitudinal Study of Ageing ', Experimental Gerontology, vol. 88, pp. 51-58 . https://doi.org/10.1016/j.exger.2016.12.013
Pain is common in older adults, is frequently experienced as stressful, and is associated with increased morbidity and mortality. Stress regulatory systems are adaptive to challenge and change, allostasis, until demands exceed the adaptive capacity c
Autor:
James L. Kirkland, Allyson K. Palmer
Publikováno v:
Experimental Gerontology. 86:97-105
Adipose tissue dysfunction occurs with aging and has systemic effects, including peripheral insulin resistance, ectopic lipid deposition, and inflammation. Fundamental aging mechanisms, including cellular senescence and progenitor cell dysfunction, o
Autor:
Horvat, P, Gardiner, J, Kubinova, R, Pajak, A, Tamosiunas, A, Schöttker, B, Pikhart, H, Peasey, A, Jansen, E, Bobak, M
Publikováno v:
Experimental Gerontology
Background Nutrient status of B vitamins, particularly folate and vitamin B-12, may be related to cognitive ageing but epidemiological evidence remains inconclusive. Objective The aim of this study was to estimate the association of serum folate and
Autor:
Osigbemhe Iyalomhe, Thomas O. Obisesan, Sheree M. Johnson, Oyonumo Ntekim, Yuanxiu Chen, Vernon Bond, Joanne S. Allard, James Li, David Goerlitz
Publikováno v:
Experimental Gerontology. 69:159-169
There is considerable support for the view that aerobic exercise may confer cognitive benefits to mild cognitively impaired elderly persons. However, the biological mechanisms mediating these effects are not entirely clear. As a preliminary step towa
Autor:
Tucker J. Piergallini, Joanne Turner
Publikováno v:
Experimental Gerontology
Growing old is associated with an increase in the basal inflammatory state of an individual and susceptibility to many diseases, including infectious diseases. Evidence is growing to support the concept that inflammation and disease susceptibility in
Publikováno v:
Experimental Gerontology
The ability of the human immune system to repel infections is drastically diminished with age. Elderly individuals are more susceptible to new threats and are less able to control endogenous infections. The thymus, which is the sole source of new T c