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Autor:
Qiuzhi Gao, Linjing Cui, Chao Huang, Zhihong Chen, Xin Wang, Shaodi Wen, Yuanyuan Zhao, Mei Wang, Bo Shen, Wei Zhu
Publikováno v:
Experimental cell research. 422(1)
CD276 has been studied in a variety of cancers and diseases, but its regulatory mechanisms in gastric cancer is still unclear. Mesenchymal stem cells (MSCs), one of the important members of tumor microenvironment, play an important role in the occurr
Publikováno v:
Experimental cell research. 422(1)
Colorectal cancer (CRC) is a common malignant tumor of digestive system. Its incidence rate and mortality rate ranks the third among all the malignant tumors. The objective of this study was to explore the role of β-catenin in the CRC progression. T
Publikováno v:
Experimental cell research. 421(1)
Cervical cancer is a major gynecological tumor worldwide. Unfortunately, the molecular mechanisms involved in cervical cancer tumorigenesis still requires more clarification. Lysophosphatidylcholine acyltransferase 1 (LPCAT1), an enzyme involved in p
Autor:
Xiaoli Long, Yukun Hu, Shiyu Duan, Xuming Liu, Wenqing Huang, Xiaoting Liu, Qiong Xu, Wen Song, Jun Zhou
Publikováno v:
Experimental cell research. 421(1)
MRG domain binding protein (MRGBP) has been proposed to participate in the development of multiple tumors. However, the role of MRGBP in colorectal cancer (CRC) still remains largely unknown. Here, we found that MRGBP expression is significantly elev
Publikováno v:
Experimental cell research. 420(1)
Adult fibrosarcoma is an aggressive subtype of soft tissue sarcoma (STS), in which high expression of KIF20A indicates a poor prognosis. However, the precise role of KIF20A in fibrosarcoma progression remains unknown. In this study, we initially exam
Autor:
Fan, Wu, Fuju, Tian, Chuanmei, Qin, Xiaoli, Qin, Weihong, Zeng, Xiaorui, Liu, Cailian, Chen, Yi, Lin
Publikováno v:
Experimental Cell Research. 422:113428
Adequate proliferation and migration of placental trophoblasts is the prerequisite of a successful pregnancy. Peroxiredoxin2 (Prdx2) is a multi-functional gene involved in various signal events to maintain essential biological functions and normal ce
Publikováno v:
Experimental cell research. 416(2)
Rab22a, a member of the proto-oncogene RAS family, belongs to the Rab5 subfamily. It participates in early endosome formation and regulates vesicle trafficking. The relationship between Rab22a and tumorigenesis remains elusive. In non-small cell lung
Autor:
Fangting Liu, Zhehao Shi, Wenming Bao, Jiuyi Zheng, Kaiyu Chen, Zhihui Lin, Hao-Nan Song, Xin Luo, Qiantong Dong, Lei Jiang, Yi Wang, Gang Chen, Xiaolei Chen
Publikováno v:
Experimental cell research. 415(2)
ZIC2 is involved in the tumor progression of many types of cancers. The role of ZIC2 in the metastasis of colorectal cancer and its mechanism are not yet clear. In this study, we found that high ZIC2 expression was not only associated with poor progn
Publikováno v:
Experimental Cell Research. 381:201-207
Metastasis remains the primary cause of cancer mortality. Throughout the process of metastasis, cancer cells experience mechanical forces, which may turn out to be the key towards their migratory, homeostatic and survival characteristics. However, th
Publikováno v:
Experimental cell research. 417(1)
Breast cancer, the most prevalent malignancy in women, is also the leading cause of cancer-related deaths in women worldwide. The activation of the Wnt pathway plays a pivotal role in the metastatic abilities of breast cancer. In this study, IL1F6, M