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Autor:
Michael Melter, Anja K. Wege, R Dayoub, Gerhard Liebisch, Sabrina Krautbauer, Sara Ibrahim, Thomas S. Weiss
Publikováno v:
Experimental Cell Research. 374:189-197
Cholestasis represents pathophysiologic syndromes defined as an impaired bile flow from the liver. As an outcome, bile acids accumulate and promote hepatocytes injury followed by liver cirrhosis and liver failure. Bile acids induce apoptosis, ER stre
Publikováno v:
Experimental Cell Research. 370:434-443
Hydrogen sulfide (H2S) prevents endothelial cells damage and P-selectin of platelets promotes neutrophils extracellular traps (NETs) formation. However, how sodium hydrosulfide (NaHS), a donor that produces H2S regulates the activation of platelets a
Publikováno v:
Experimental Cell Research. 407:112784
Inflammation is an essential factor contributing to sepsis-induced endothelial cell (EC) activation. Interleukin-35 (IL-35) is an anti-inflammatory/immunosuppressive cytokine that exerts protective effects on many inflammatory diseases. In this study
Autor:
Mingjun Zhang, Zongjie Fu, Wen Zhang, Hongkun Ma, Wei-Tang Liao, Yong-Xi Chen, Dan Wen, Fangfang Zhou, Yan-Fang Zou
Publikováno v:
Experimental Cell Research. 360:292-302
Oxidative stress was predominantly involved in the pathogenesis of acute kidney injury (AKI). Recent studies had reported the protective role of specific microRNAs (miRNAs) against oxidative stress. Hence, we investigated the levels of miR140-5p and
Autor:
Lu Zhang, Xueying Li
Publikováno v:
Experimental Cell Research. 396:112159
Traumatic optic neuropathy is a common clinical problem. Damage to the optic nerve leads to shear stress and triggers secondary swelling within the optic canal. The study aims to explore the role of the inflammatory response following optic nerve inj
Autor:
Partha Roy, Shruti Sharan, Kumar Nikhil, Naganjaneyulu Bodipati, A.K. Chakraborty, Rama Krishna Peddinti
Publikováno v:
Experimental Cell Research. 320:311-328
Naturally occurring pterostilbene (PTER) and isothiocyanate (ITC) attract great attention due to their wide range of biological properties, including anti-cancer, anti-leukemic, anti-bacterial and anti-inflammatory activities. A novel class of hybrid
Autor:
Shelly C. Lu, Pasquale Giordano, Minjung Ryoo, José M. Mato, Anna Skay, Maria Lauda Tomasi, Ivan Tomasi
Publikováno v:
Experimental Cell Research. 319:1902-1911
Methionine adenosyltransferase (MAT) is an essential enzyme that is responsible for the biosynthesis of S-adenosylmethionine (SAMe), the principal methyl donor and precursor of polyamines. MAT1A is expressed in normal liver and MAT2A is expressed in
Autor:
Cecilia Balbi, Paola Barboro, Erica Repaci, Cristina D'Arrigo, Luca Bagnasco, Paola Orecchia, Barbara Carnemolla, Eligio Patrone
Publikováno v:
Experimental cell research 315 (2009): 226–239. doi:10.1016/j.yexcr.2008.10.017
info:cnr-pdr/source/autori:Barboro P.; D'Arrigo C.; Repaci E.; Bagnasco L.; Orecchia P.; Carnemolla B.; Patrone E.; Balbi C./titolo:Proteomic analysis of the nuclear matrix in the early stages of rat liver carcinogenesis: identification of differentially expressed and MAR-binding proteins/doi:10.1016%2Fj.yexcr.2008.10.017/rivista:Experimental cell research/anno:2009/pagina_da:226/pagina_a:239/intervallo_pagine:226–239/volume:315
info:cnr-pdr/source/autori:Barboro P.; D'Arrigo C.; Repaci E.; Bagnasco L.; Orecchia P.; Carnemolla B.; Patrone E.; Balbi C./titolo:Proteomic analysis of the nuclear matrix in the early stages of rat liver carcinogenesis: identification of differentially expressed and MAR-binding proteins/doi:10.1016%2Fj.yexcr.2008.10.017/rivista:Experimental cell research/anno:2009/pagina_da:226/pagina_a:239/intervallo_pagine:226–239/volume:315
Tumor progression is characterized by definite changes in the protein composition of the nuclear matrix (NM). The interactions of chromatin with the NM Occur via specific DNA sequences called MARS (matrix attachment regions). In the present study, we
Publikováno v:
Experimental Cell Research. 314:2774-2787
Beta-catenin plays a role in intracellular adhesion and regulating gene expression. The latter role is associated with its oncogenic properties. Phosphorylation of beta-catenin controls its intracellular expression but mechanism/s that regulates the
Publikováno v:
Experimental Cell Research. 308:394-406
SCA-9 cell line was developed from an induced tumor of mouse submandibular gland. We have studied some of the phenotypic characteristics of SCA cells cultured on different matrices. On plastic surface, the cells grow as a monolayer; on matrigel, they