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Autor:
Fan, Wu, Fuju, Tian, Chuanmei, Qin, Xiaoli, Qin, Weihong, Zeng, Xiaorui, Liu, Cailian, Chen, Yi, Lin
Publikováno v:
Experimental Cell Research. 422:113428
Adequate proliferation and migration of placental trophoblasts is the prerequisite of a successful pregnancy. Peroxiredoxin2 (Prdx2) is a multi-functional gene involved in various signal events to maintain essential biological functions and normal ce
Autor:
Rui Wang, Shuaichen Sun, Zizhuo Wang, Xiaoxiang Xu, Tao Jiang, Huanzhong Liu, Xiaohui Li, Zhenhua Ren
Publikováno v:
Experimental Cell Research. 418:113267
Glioma is the most common primary malignant intracranial tumor in the population, and is often associated with abundant angiogenesis. However, how angiogenesis is regulated during glioma progression is still poorly understood. Data mining of cancer p
Publikováno v:
Experimental Cell Research. 418:113270
Hemangioma (HA) is a neoplastic disease derived from vascular endothelial cells. Recently, SASH1 has been identified as a tumor suppressor gene. The purpose of this study was to investigate the role and regulatory mechanism of SASH1 in HA. RT-PCR and
Autor:
Xing Wang, Xinwei Chen, Yuanyuan Liu, Shan Huang, Jian Ding, Baoxin Wang, Pin Dong, Zhenfeng Sun, Lixiao Chen
Publikováno v:
Experimental Cell Research. 417:113220
Human CUB and Sushi multiple domains (CSMD1) is considered a crucial role in cancer progression, but the specific function in esophageal squamous cell carcinoma (ESCC) is not clear. Understanding the role of CSMD1 in ESCC progression may lead to a no
Publikováno v:
Experimental Cell Research. 417:113194
Breast cancer (BC) is the second cause of cancer-related mortality in women. Seizure related 6 homolog like 2 (SEZ6L2), a protein presented on cell surface, is involved in tumor development. It was found to be highly expressed in BC, however, its rol
Publikováno v:
Experimental Cell Research. 416:113158
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant diseases in the world. Although the somatic alterations have been fully identified, there are still no targeted drugs at present. Our previous studies revealed that loss of
Publikováno v:
Experimental Cell Research. 416:113159
Hypoxia is an important cause of cervical lymph nodes metastasis and recurrence of thyroid cancer, but its specific mechanism remains unclear. In the present study, we constructed a hypoxia model of thyroid cancer cells and explored the potential tar
Autor:
Jinxiu Sheng, Mingxia Zhou, Chang Wang, Jinlin Jia, Jie Chu, Chenxi Ju, Junhu Wan, Jing He, Fucheng He
Publikováno v:
Experimental Cell Research. 415:113117
Mounting evidence suggests that long non-coding RNAs play a critical role in the occurrence and development of human malignancies. Nonetheless, it remains unknown whether Gamma-Butyrobetaine Hydroxylase 1-Antisense RNA 1 (BBOX1-AS1) participates in t
Publikováno v:
Experimental Cell Research. 381:201-207
Metastasis remains the primary cause of cancer mortality. Throughout the process of metastasis, cancer cells experience mechanical forces, which may turn out to be the key towards their migratory, homeostatic and survival characteristics. However, th
Publikováno v:
Experimental Cell Research. 380:36-46
Pulmonary arterial hypertension (PAH) is a diffuse pulmonary microvascular remodeling disease accompanied by malignant proliferation of pulmonary artery smooth muscle cells (PASMCs), which causes persistent pulmonary artery pressure elevation, right