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Autor:
AbdelMoneim M Naguib, Sara M. Mohamed, Tahany A.A. Aly, Emam A. Abdel-Rahim, Marwa S. Khattab
Publikováno v:
Exp Biol Med (Maywood)
Increased environmental pollution and unhealthy lifestyle are blamed for escalated chronic diseases. Exposure to aflatoxins was recently suggested to have a role in the increased incidence of type 2 diabetes mellitus. Diet modification and consumptio
Autor:
Di Chang, Shi-Jun Zhang, Chun-Qiang Lu, Yuan-Cheng Wang, Yu Cai, Zhen Zhao, Shenghong Ju, Tingting Xu, Shudan Min
Publikováno v:
Exp Biol Med (Maywood)
Chronic kidney disease (CKD) is a major contributor to the development of heart failure with preserved ejection fraction (HFpEF), whereas the underlying mechanism of cardiorenal HFpEF is still elusive. The aim of this study was to investigate the rol
Autor:
Nella C. Delva, Gregg D. Stanwood
Publikováno v:
Exp Biol Med (Maywood)
Major depressive disorder (MDD or depression) is a debilitating neuropsychiatric syndrome with genetic, epigenetic, and environmental contributions. Depression is one of the largest contributors to chronic disease burden; it affects more than one in
Publikováno v:
Experimental Biology and Medicine
Acute respiratory disease caused by a novel coronavirus (SARS-CoV-2) has spread all over the world, since its discovery in 2019, Wuhan, China. This disease is called COVID-19 and already killed over 1 million people worldwide. The clinical symptoms i
Autor:
Guoxiang Cai, Xiaotong Wang, Jianwen Liu, Renjie Wang, Changfeng Song, Xin Liang, Qianyi Gong
Publikováno v:
Exp Biol Med (Maywood)
Peritoneum is one of the most common metastatic sites of colorectal cancer (CRC). It has been reported that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) prolongs the lifespan of patients with peritoneal carcin
Publikováno v:
Exp Biol Med (Maywood)
Timothy syndrome is a rare disorder caused by CACNA1C gene mutations and characterized by multi-organ system dysfunctions, including ventricular arrhythmias, syndactyly, dysmorphic facial features, intermittent hypoglycemia, immunodeficiency, develop
Publikováno v:
Exp Biol Med (Maywood)
Vincristine, a vinca alkaloid, is widely used in many hematologic disorders and pediatric cancers, and acts by binding to the tubulin protein, to inhibit effective cell division. Vincristine-induced anemia has been observed, but its mechanism is not
Autor:
Thiago Macêdo Lopes Correia, Ana Carolina de Bragança, Amélia Cristina Mendes de Magalhães, Cláudia Silva Souza, Daniele Canale, Geovanildo Nascimento Viana, Liliany Souza de Brito Amaral, Márcio Vasconcelos Oliveira, Bianca Silva de Sousa Oliveira, Telma de Jesus Soares, Rildo Aparecido Volpini
Publikováno v:
Exp Biol Med (Maywood)
This study evaluated the effects of moderate regular physical exercise on lipid peroxidation, inflammation and renal function and structure in streptozotocin (STZ)-induced ovariectomized diabetic rats. Twenty-four Wistar rats were anesthetized and su
Publikováno v:
Exp Biol Med (Maywood)
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by persistent synovitis, autoantibodies, and systemic inflammation. This study evaluates the possible antirheumatic effect of isoflavone-free soy protein isolate (SPI) in a
Publikováno v:
Experimental Biology and Medicine. 244:372-379
Six million cancer patients worldwide receive radiotherapy, either alone or in combination with other cancer treatments annually. The purpose of this study was to investigate, at the structural and molecular levels, the protective effect of N-acetylc