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Publikováno v:
Experimental and Therapeutic Medicine
Expression of miR-28-3p in patients with Alzheimer's disease (AD) before and after treatment and clinical value of miR-28-3p were determined. There were three groups: 68 AD patients treated with donepezil combined with basic therapy in The People's H
Publikováno v:
Experimental and Therapeutic Medicine
Clinical efficacy of atorvastatin calcium combined with aspirin in patients with acute ischemic stroke (AIS) and its effect on neutrophils to lymphocytes ratio (NLR) and interleukin-33 (IL-33) were investigated. In total, 108 patients with AIS in Luo
Publikováno v:
Experimental and Therapeutic Medicine
Fetal goitrous hypothyroidism is a rare condition associated with important obstetrical, neonatal complications, and neurodevelopmental impairments. Prenatal treatment remains controversial, and the risk to benefit ratio must be accurately assessed a
Autor:
Li-Sheng Wang, Ding‑Guo Zhang, Feng Xiong, Jun Yao, Zhi‑Chao Yu, De-Feng Li, Xin Chang, Zheng‑Lei Xu, Jian‑Yao Wang, Ting-Ting Liu, Xue Fang, Ming‑Han Luo, Cheng Wei
Publikováno v:
Experimental and Therapeutic Medicine
Current guidelines recommend temporary cessation of clopidogrel for 7-10 days for patients on clopidogrel undergoing colonoscopy with polypectomy. However, recent prospective randomized controlled trials have advocated for uninterrupted clopidogrel,
Autor:
Elena Porumb-Andrese, Alina Ioana Grăjdeanu, Adriana Ionela Pătrașcu, Laura Gheucă Solovăstru, Cristina Grechin, Dan Vâță
Publikováno v:
Experimental and Therapeutic Medicine
Substantial research has focused on the presence of biomarkers involved in both the pathogenesis of psoriasis and its comorbidities. The identification of these biomarkers has a crucial role in establishing the diagnosis and prognosis, in understandi
Publikováno v:
Experimental and Therapeutic Medicine
Effect of imatinib on rats with spinal cord injury (SCI) was investigated through the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. Forty-eight Sprague-Dawley rats were randomly divided into sham operat
Publikováno v:
Experimental and Therapeutic Medicine
The present study aimed to investigate the regulatory mechanisms by which interleukin (IL)-22 regulates cisplatin (DDP) sensitivity in osteosarcoma cells. Firstly, reverse transcription-quantitative (RT-q) PCR and western blotting demonstrated that I
Both UFH and NAH alleviate shedding of endothelial glycocalyx and coagulopathy in LPS-induced sepsis
Autor:
Haixiao Xu, Xiaozhi Wang, Haoran Hu, Bingyan Xia, Dong Hao, Tao Wang, Jiankui Li, Guiqing Kong, Shasha Han, Xiangyong Liu, Weiwei Zhu, Xiao Huang
Publikováno v:
Experimental and Therapeutic Medicine
Sepsis commonly progresses to disseminated intravascular coagulation and induces the activation of heparanase (HPA) and the shedding of endothelial glycocalyx constituents, including syndecan-1 (SDC-1) and heparan sulphate (HS). However, the degradat
Publikováno v:
Experimental and Therapeutic Medicine
Efficacy of levetiracetam (LEV) combined with sodium valproate (SV) on pediatric epilepsy and its effect on serum miR-106b in children were investigated. One hundred and twenty children with epilepsy in Xuzhou Children's Hospital from July 2015 to Ju
Publikováno v:
Experimental and Therapeutic Medicine
Sphingosine-1-phosphate (S1P) has been reported to enhance the function of islet β-cells, providing a potential therapeutic target for diabetes mellitus. In the present study, the effects of S1P on the proliferation and apoptosis of β-cells in type