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Publikováno v:
Experimental and Therapeutic Medicine
Doxorubicin (DOX) has been widely employed to treat cancer, particularly solid tumors and hematological malignancies, owing to its high efficacy; however, chemotherapy has been indicated to be cardiotoxic and induce adverse effects, including mitocho
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to investigate the potential therapeutic effects of molecular hydrogen on type 2 diabetes mellitus (T2DM) in rats. Following maintenance on a high-fat diet for 4 weeks, a T2DM model was established using an injection
Publikováno v:
Experimental and Therapeutic Medicine
Protective effect of fluvastatin (Flu) on myocardial cells in mice with acute myocardial infarction (AMI) and the mechanism were explored. Forty C57B/L6 mice in similar physiological status were selected and randomly divided into sham operation (Sham
Publikováno v:
Experimental and Therapeutic Medicine
Effect of imatinib on rats with spinal cord injury (SCI) was investigated through the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. Forty-eight Sprague-Dawley rats were randomly divided into sham operat
Publikováno v:
Experimental and Therapeutic Medicine
Angiotensin-converting enzyme inhibitors (ACEIs) can reduce urinary protein excretion and postpone the deterioration of renal function. However, the mechanisms of renal protection are not yet fully understood. To investigate the mechanisms of ACEIs i
Publikováno v:
Experimental and Therapeutic Medicine
Changes in the levels of serum oxidative stress indexes, gastrointestinal hormones and inflammatory factors in children with different severity of reflux esophagitis (RE) were detected. Sixty child patients diagnosed with gastroesophageal reflux dise
Autor:
Flavia Baderca, Darian Rusu, Marius Boariu, Stefan-Ioan Stratul, ER Boia, Claudia Borza, Simina Boia, Andrei Anghel, Florin George Horhat, Delia Muntean
Publikováno v:
Experimental and Therapeutic Medicine
Aim of research was to evaluate and compare the clinical and microbiological effects of two different regimens of amoxicillin (AMX) and metronidazole (MTZ) combined with non-surgical periodontal therapy in patients with chronic periodontitis (CP), an
Publikováno v:
Experimental and Therapeutic Medicine.
Hyperglycemia-induced oxidative stress and inflammation are hallmarks of liver damage in diabetes mellitus. Accumulating evidence has demonstrated that Pluchea indica leaf ethanol extract (PILE) possesses strong antioxidant and anti-inflammatory prop
Publikováno v:
Experimental and Therapeutic Medicine
Protective effects of liraglutide on H9C2 cells cultured using CoCl2 and its mechanism of action were investigated. Hypoxia model was established using CoCl2-treated H9C2 cells. With liraglutide as the treatment factor, apoptosis, changes in nitric o
Publikováno v:
Experimental and Therapeutic Medicine
Propofol is a widely used intravenous anesthetic shown to exert a cardioprotective role against oxidative stress and ischemia/reperfusion injury in rat cardiac H9c2 cells. However, the regulatory mechanisms and functions of propofol in human cardiomy