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Publikováno v:
Exp Ther Med
Curative effect of magnesium sulfate combined with nifedipine on pregnancy-induced hypertension and the effect of serum inflammatory factors were investigated. A total of 188 cases of patients were collected as the research subjects. They all had pre
Publikováno v:
Experimental and Therapeutic Medicine
Obesity results in a variety of metabolic alterations that may contribute to abnormalities in cardiac structure and function. Although metformin (Met) has been previously reported to exhibit beneficial effects against cardiomyopathy associated obesit
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to investigate the potential therapeutic effects of molecular hydrogen on type 2 diabetes mellitus (T2DM) in rats. Following maintenance on a high-fat diet for 4 weeks, a T2DM model was established using an injection
Publikováno v:
Experimental and Therapeutic Medicine
The treatment of atherosclerosis remains complex. Pitavastatin serves an important role in the prevention and treatment of atherosclerosis. The present study aimed to investigate the effects of nanoparticle (NP)-mediated delivery of pitavastatin into
Publikováno v:
Experimental and Therapeutic Medicine
Effect of imatinib on rats with spinal cord injury (SCI) was investigated through the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. Forty-eight Sprague-Dawley rats were randomly divided into sham operat
Publikováno v:
Experimental and Therapeutic Medicine
Nicorandil effects on platelet activation and myocardial antioxidant function in patients with unstable angina were studied. A total of 157 patients with unstable angina in the First People's Hospital of Foshan were selected and divided into experime
Autor:
Ziping Yao, Yanling Fu
Publikováno v:
Experimental and Therapeutic Medicine
The anti-inflammatory effects of glycyrrhizic acid (GA) against asthma have previously been reported; however, the underlying molecular mechanism of GA in asthma has not yet been elucidated. Thus, the present study aimed to determine the function and
Autor:
Zhiping Li, Yan Wang
Publikováno v:
Experimental and Therapeutic Medicine
Epilepsy is the most common chronic neurological disorder, affecting ~70 million individuals worldwide. However, approximately one-third of the patients are refractory to epilepsy medication. Of note, 100% of patients with genetic epilepsy who are re
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to investigate the protective effect of dexmedetomidine (Dex) on endothelial injury in a cecal ligation and puncture (CLP)-induced rat model of sepsis. A total of 36 male Sprague-Dawley rats were divided into three gr
Autor:
Seijirow Goya, Ryosuke Namiki, Akiko Uemura, Danfu Ma, Pitipat Kitpipatkun, Kazuhiko Suzuki, Ryou Tanaka, Tomohiko Yoshida, Katsuhiro Matsuura, Kazumi Shimada
Publikováno v:
Experimental and Therapeutic Medicine
Pulmonary hypertension (PH) is a disease with poor prognosis, and it is characterized by the progressive elevation of pulmonary vascular resistance and pressure. Various factors are associated with the pathology of PH, including AMP-activated protein