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Publikováno v:
Exp Ther Med
Curative effect of magnesium sulfate combined with nifedipine on pregnancy-induced hypertension and the effect of serum inflammatory factors were investigated. A total of 188 cases of patients were collected as the research subjects. They all had pre
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to investigate the potential therapeutic effects of molecular hydrogen on type 2 diabetes mellitus (T2DM) in rats. Following maintenance on a high-fat diet for 4 weeks, a T2DM model was established using an injection
Publikováno v:
Experimental and Therapeutic Medicine
Effect of imatinib on rats with spinal cord injury (SCI) was investigated through the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. Forty-eight Sprague-Dawley rats were randomly divided into sham operat
Publikováno v:
Experimental and Therapeutic Medicine
Breast cancer remains a worldwide public-health issue. Novel drugs that increase the sensitivity and reduce the toxic side effects of chemotherapeutic agents are urgently required. The present study investigated the effect and mechanism of the short-
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the study was to investigate the effects of tetrandrine combined with acetylcysteine on exercise tolerance, pulmonary function, transforming growth factor-β1 (TGF-β1) and matrix metalloproteinase 7 (MMP-7) in silicosis patients. A retros
Publikováno v:
Experimental and Therapeutic Medicine
Mechanism by which α-synuclein affects the progression of Parkinson's disease through Pyrin Domain Containing Protein 3 (NLRP3) was explored. Peripheral blood plasma of 40 Parkinson's disease patients and 40 normal healthy people attending the depar
Autor:
Xiaoli Liu, Qing Li, Meirong Lv, Peng Wei, Tingting Wang, Wenping Xu, Zhilong Huang, Wenjun Xia, Xinlei Chen
Publikováno v:
Experimental and Therapeutic Medicine
A number of previous studies have demonstrated that inhibiting autophagy can increase the cellular cytotoxicity of chemotherapeutic agents in urothelial cancer cells. However, the mechanistic roles of autophagy in gemcitabine (GEM) resistant bladder
Publikováno v:
Experimental and Therapeutic Medicine. 12:4035-4040
Taraxasterol is an effective component of dandelion that has anti-inflammatory effects in vivo and in vitro. The present study was performed to explore whether taraxasterol exhibits a protective effect against rheumatoid arthritis through the modulat
Publikováno v:
Experimental and Therapeutic Medicine
Neurons undergo degeneration, apoptosis and death due to ischaemic stroke. The present study investigated the effect of Sijunzi decoction (SJZD), a type of traditional Chinese medicine known as invigorating spleen therapy, on anoikis (a type of apopt
Autor:
Mehmet Erman Erdemli, Onural Ozhan, Sami Akbulut, Yilmaz Bilgic, Zeynep Aksungur, Nigar Vardi, Hakan Parlakpinar, Yusuf Turkoz
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to investigate the protective effect of dexpanthenol (Dexp) against cisplatin (Cis)-induced hepatotoxicity. Thirty-two Sprague Dawley rats were divided into four groups: Control group (n=8), Dexp group (n=8, 500 mg/kg