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Autor:
Jian Wang, Xiaoxia Wang
Publikováno v:
Experimental and Molecular Pathology. 107:179-183
We present two cases of sclerosing epithelioid fibrosarcoma (SEF) that arose primarily in the kidney. The tumor in both cases was located at the upper pole of the kidney. Clincially, they were suspected as renal cell carcinomas. However, histological
Autor:
Nathaniel Melling, Jakob R. Izbicki, Alexander T. El Gammal, Kai Bachmann, Oliver Mann, Florian Gebauer, Maximillian Bockhorn, Matthias Reeh, Katharina Grupp, Daniel Perez
Publikováno v:
Experimental and Molecular Pathology. 107:51-56
Expression of the retinoic acid-induced protein 3 (RAI3) has been suggested to predict clinical outcome in a variety of malignancies. However, its role in esophageal cancers remains unclear. Immunohistochemical RAI3 staining was analyzed on tissue mi
Autor:
Sakiko Masuda, Xiao-yu Jia, Ming-Hui Zhao, Daigo Nakazawa, Utano Tomaru, Zhao Cui, Satoshi Tanaka, Akihiro Ishizu, Yuka Nishibata, Mandkhai Nergui, Kimimasa Nakabayashi
Publikováno v:
Experimental and Molecular Pathology. 107:165-170
The major epitopes recognized by autoantibodies in anti-glomerular basement membrane (GBM) disease are found in the α3-subunit non-collagenous domain of type IV collagen [α3(IV)NC1], which is present in the glomerular and alveolar basement membrane
Autor:
Cristian Augusto Ostjen, Norma Possa Marroni, Josieli Raskopf Colares, Carlos Gustavo Sakuno Rosa, Renata Minuzzo Hartmann, Elizângela Gonçalves Schemitt
Publikováno v:
Experimental and Molecular Pathology. 106:52-59
In recent decades, the number of people who practice sports has grown exponentially, increasing the number of muscular injuries. Trauma injury occurs when the muscle is exposed to a sudden compression force. Melatonin (MLT) has often been cited in th
Autor:
Vladan Živaljević, Ilona Đorić, Sonja Selemetjev, Tijana Išić Denčić, Aleksandar Bartolome, Svetislav Tatic, Dubravka Cvejic
Publikováno v:
Experimental and Molecular Pathology. 105:181-189
We have evaluated the clinical significance of deregulated expression of β-catenin and epidermal growth factor receptor (EGFR) during papillary thyroid carcinoma (PTC) progression. Immunohistochemical expression of β-catenin and EGFR was analyzed i
Publikováno v:
Exp Mol Pathol
Stem cell factor (SCF) is an essential cytokine during development and is necessary for gametogenesis, hematopoiesis, mast cell development, stem cell function, and melanogenesis. Here, we measure SCF concentration and distribution in adult humans an
Autor:
Yasser S. Saraya, Rham Z. Ahmed, Nabila Hefzi, Mohamed Ali Alabiad, Gamal Osman, Amr Abd Almohsen Alnemr, Amany Mohamed Shalaby, Ola A. Harb
Publikováno v:
Experimental and Molecular Pathology. 122:104670
Background there is a need for novel biomarkers and targeting therapies for predicting Endometrial carcinoma (EC) progression and recurrence. TMEFF2 is a gene that was found to play a role in EMT. SMOC-2 is expressed in embryogenesis and it was ident
Autor:
Soma Saeed, A.K. Sheikh, Kashif Bashir, Romana Sarwar, Mahmood Akhtar Kayani, Ishrat Mahjabeen
Publikováno v:
Experimental and Molecular Pathology. 102:446-454
Aims RAD51 participates in homologous recombination repair (HRR) of double-stranded DNA breaks (DSBs) which may cause genomic instability and cancer. The aim of this study was to investigate RAD51 gene expression at transcriptional and translational
Autor:
Céline Chauleur, Jean Michel Prades, Michel Peoc'h, Vanessa Da Cruz, Georgia Karpathiou, Mousa Mobarki, Jean Marc Dumollard, Fabien Forest, Francois Casteillo
Publikováno v:
Experimental and Molecular Pathology. 102:230-236
Background FOXA1 is a major transcription factor involved in the action of human papilloma virus (HPV). However, it has been never studied in HPV-associated tumors. Aim of the study To investigate its expression in cervical and head and neck tumors.
Autor:
Satoshi Maruyama, Bo Xu, Takashi Saku, Hamzah Babkair, Tadashi Yamamoto, Manabu Yamazaki, Yoshimasa Sumita, Tatsuya Abé, Jun Cheng
Publikováno v:
Experimental and Molecular Pathology. 102:327-336
Oral squamous cell carcinomas (SCCs) are frequently associated with pre-invasive lesions including carcinoma in-situ (CIS), and CISs further form lateral interfaces against surrounding normal or dysplastic epithelia (ND). At the interface where kerat