Zobrazeno 1 - 10
of 17
pro vyhledávání: '"du Bois, A"'
Autor:
David J. Lederer, Williamson Z. Bradford, Dominique Valeyre, Paul W. Noble, Talmadge E. King, Lisa Lancaster, Steven D. Nathan, Elizabeth A. Fagan, Robert S. Fishman, Ian Glaspole, Carlo Albera, Ulrich Costabel, Roland M. du Bois, Jonathan A. Leff, Carlos Alberto de Castro Pereira, Jeffrey J. Swigris, Marilyn K. Glassberg
Publikováno v:
European Respiratory Journal. 47:243-253
Pirfenidone is an antifibrotic agent that has been evaluated in three multinational phase 3 trials in patients with idiopathic pulmonary fibrosis (IPF). We analysed pooled data from the multinational trials to obtain the most precise estimates of the
Autor:
V. Kolek, Eva Kriegova, R. Fillerova, Frantisek Mrazek, T. Tomankova, T. Tichy, B. Hutyrova, Martin Petrek, R M du Bois
Publikováno v:
European Respiratory Journal. 38:1136-1144
Upregulation of genes for interferon (IFN)-γ and CXC chemokine receptor (CXCR)3 expression, two crucial molecules in sarcoid inflammation and granuloma formation, is directly controlled by the T-helper (Th)1 transcription factor T-bet (T-box, expres
Autor:
AU Wells, David M. Hansell, Carol M. Black, C Anagnostopoulos, R M du Bois, Christopher P. Denton, Rachel K. Hoyles, Sujal R. Desai, Nicole S. L. Goh, Hiroe Sato
Publikováno v:
European Respiratory Journal. 38:184-190
Epithelial injury contributes to pathogenesis in idiopathic pulmonary fibrosis (IPF) but its role in the interstitial lung disease (ILD) of systemic sclerosis (SSc) is uncertain. We quantified the prognostic significance of inhaled technetium-99m ((9
Autor:
AU Wells, David M. Hansell, Derek Cramer, C J Zappala, T. V. Colby, Andrew G. Nicholson, Panagiota Latsi, EA Renzoni, R M du Bois
Publikováno v:
European Respiratory Journal. 35:830-836
In therapeutic studies in idiopathic pulmonary fibrosis (IPF), the low prevalence of significant change in pulmonary functional tests (PFTs) has been a major constraint. The prognostic value of "marginal" changes in PFTs in IPF and fibrotic non-speci
Autor:
Kenneth I. Welsh, AU Wells, Atiyeh M Abdallah, R M du Bois, Horace R T Williams, Tariq Ahmad, Timothy R. Orchard, Susan J. Copley, Sujal R. Desai, Hiroe Sato, Paolo Spagnolo
Publikováno v:
European Respiratory Journal. 35:324-330
Sarcoidosis and Crohn's disease are heterogeneous systemic diseases characterised by granulomatous inflammation. Caspase recruitment domain (CARD)15 is a major susceptibility gene for Crohn's disease, and specifically for ileal and fibrostenotic subt
Autor:
Panagiotis Pantelidis, Srihari Veeraraghavan, Patricia L Haslam, AU Wells, EA Renzoni, Andrew G. Nicholson, R M du Bois, Panagiota Latsi, Thomas V. Colby
Publikováno v:
European Respiratory Journal. 22:239-244
Idiopathic pulmonary fibrosis (IPF), which has the histological pattern of usual interstitial pneumonia (UIP), is a progressive interstitial lung disease with a poor prognosis. Idiopathic interstitial pneumonias with a histological pattern of nonspec
Publikováno v:
European Respiratory Journal. 20:1206-1212
The chemokines RANTES (regulated on activation, T-cell expressed and secreted; CC chemokine ligand (CCL)-5) and monocyte inflammatory protein (MIP)-1alpha (CCL-3) have been implicated in the development of alveolitis in pulmonary sarcoidosis. The nov
Autor:
R M du Bois, S D Nathan
Publikováno v:
European Respiratory Journal. 38:1002-1004
Idiopathic pulmonary fibrosis (IPF) is a disease with a dismal prognosis and a median survival of only 2–3 yrs. There are no licensed medical therapies in the USA and the only care options that are endorsed by the most recent consensus guidelines a
Autor:
Stefan J. Marciniak, Peter Goldstraw, Zoe Daniil, FC Gilchrist, Panagiotis Pantelidis, U. Pastorino, R M du Bois
Publikováno v:
European Respiratory Journal. 16:67-73
The aim of this study was to investigate the effect on lung function of lung biopsy used in the diagnosis of diffuse lung disease carried out by an open procedure or by video-assisted thoracoscopy. One hundred and sixteen patients with diffuse lung d
Publikováno v:
European Respiratory Journal. 13:133-136
This study evaluated the utility of the clearance time of inhaled diethylenetriamine pentaacetate (DTPA) to distinguish pulmonary vascular disease from early fibrosing alveolitis (FA) in patients with systemic sclerosis (SSc). It was hypothesized tha