Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Roy H. Perlis"'
Autor:
Ian W. Craig, Charles Curtis, Glyn Lewis, Roy H. Perlis, Anne Farmer, Ole Mors, Richard M. Weinshilboum, Michael Conlon O'Donovan, Hamel Patel, Katherine J. Aitchison, Koen Schruers, Anna Placentino, Gerome Breen, Chiara Fabbri, Katherine E. Tansey, Daniel Souery, Gregory D. Jenkins, Neven Henigsberg, Sang Hyuk Lee, Joanna Hauser, Joanna M. Biernacka, Cathryn M. Lewis, Rudolf Uher, Marcella Rietschel, Stephen Newhouse, Wolfgang Maier, Peter McGuffin
Publikováno v:
Fabbri, C, Tansey, K E, Perlis, R H, Hauser, J, Henigsberg, N, Maier, W, Mors, O, Placentino, A, Rietschel, M, Souery, D, Breen, G, Curtis, C, Lee, S-H, Newhouse, S, Patel, H, O'Donovan, M, Lewis, G, Jenkins, G, Weinshilboum, R M, Farmer, A, Aitchison, K J, Craig, I, McGuffin, P, Schruers, K, Biernacka, J M, Uher, R & Lewis, C M 2018, ' Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects : Meta-analysis of data from genome-wide association studies ', European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol. 28, no. 8, pp. 945-954 . https://doi.org/10.1016/j.euroneuro.2018.05.009
European Neuropsychopharmacology, 28(8), 945-954. Elsevier
European Neuropsychopharmacology, 28(8), 945-954. Elsevier
Cytochrome (CYP) P450 enzymes have a primary role in antidepressant metabolism and variants in these polymorphic genes are targets for pharmacogenetic investigation. This is the first meta-analysis to investigate how CYP2C19 polymorphisms predict cit
Autor:
Shawn N. Murphy, Victor M. Castro, Chia-Yen Chen, Pamela Sklar, Vivian S. Gainer, Roy H. Perlis, Phil Lee, Tianxi Cai, Jessica Minnier, Jordan W. Smoller
Publikováno v:
European Neuropsychopharmacology. 29:S968-S969
Background Bipolar Disorder (BD) is a heritable mood disorder with about 1% lifetime prevalence in general population. Many BD-associated loci have been identified through Genome-Wide Association Studies (GWAS). However, larger sample size and more d
Autor:
Pieter J. Vuijk, Sheila M. O'Keefe, Joanna Martin, Ellen B. Braaten, Alysa E. Doyle, Anna Samkavitz, Michael R. Capawana, Jordan W. Smoller, Roy H. Perlis, Hannah S. Lind, Stephen V. Faraone, Brenda A. Lee
Publikováno v:
European Neuropsychopharmacology. 29:S811-S812
Background A recent genome-wide association analysis has identified specific susceptibility variants and a substantial polygenic component for Attention-Deficit/Hyperactivity Disorder (ADHD). Given that emerging risk variants are unlikely to track pr
Autor:
Richard M. Weinshilboum, Joanna M. Biernacka, Chiara Fabbri, Rudolf Uher, Gendep Investigators, Roy H. Perlis, Katherine E. Tansey, Cathryn M. Lewis, Gerome Breen
Publikováno v:
European Neuropsychopharmacology. 29:S808
Background Major Depressive Disorder (MDD) is a leading cause of disability-adjusted life years worldwide. Genetic polymorphisms may have the potential to guide antidepressant treatment to increase current remission rates. Cytochrome P450 (CYP450) en
Autor:
Michael Conlon O'Donovan, Charles Curtis, S. Newhouse, Rudolf Uher, O. Mors, Guido Bondolfi, Anna Placentino, Glyn Lewis, Katherine J. Aitchison, Hamel Patel, Ian W. Craig, W. Maier, Roy H. Perlis, M. Rietschel, Gerome Breen, Joanna M. Biernacka, Anne Farmer, Richard M. Weinshilboum, Katherine E. Tansey, Chiara Fabbri, L. Sang-Hyuk, Nader Perroud, Daniel Souery, Neven Henigsberg, Joanna Hauser, M. Guipponi, Cathryn M. Lewis, P. McGuffin
Publikováno v:
European Neuropsychopharmacology. 27:S582-S583
Autor:
T. Dose, Thomas Bettecken, Stephan Ripke, Florian Holsboer, Susanne Lucae, Peter McGuffin, Elisabeth B. Binder, Daria Salyakina, Benno Pütz, Simone Reppermund, Torsten Klengel, Martin A. Kohli, Johannes M. Hennings, Marcus Ising, Roy H. Perlis, Steven P. Hamilton, Josef Zihl, Rudolf Uher, Tanja Brückl, Paul G. Unschuld, Bertram Müller-Myhsok, Manfred Uhr, Stefan Kloiber
Publikováno v:
European Neuropsychopharmacology. 23:653-662
Leptin, a peptide hormone from adipose tissue and key player in weight regulation, has been suggested to be involved in sleep and cognition and to exert antidepressant-like effects, presumably via its action on the HPA-axis and hippocampal function.