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Publikováno v:
European Neurology. 73:360-366
Background: Animal studies suggest that statins may have a protective effect on Alzheimer's disease (AD), but some clinical trials have reported negative results. Objective: To evaluate the efficacy and safety of statins in the treatment of AD. Metho
Autor:
Francesco Patti
Publikováno v:
European neurology. 75
Background: In Italy, all prescriptions for THC:CBD oromucosal spray for treatment of multiple sclerosis (MS) spasticity are linked to the official Agenzia Italiana del Farmaco (AIFA) web-based registry, which tracks the effectiveness and tolerabilit
Autor:
Oscar Fernández
Publikováno v:
European Neurology. 72:9-11
Background: Most patients with multiple sclerosis (MS) experience spasticity as the clinical course evolves. Associated symptoms include (often painful) spasms, urinary dysfunction and sleep disturbances. THC:CBD oromucosal spray (Sativex®) is appro
Autor:
Oscar Fernández
Publikováno v:
European Neurology. 72:12-14
Background: Clinical trials demonstrate the efficacy and tolerability of an intervention under experimental conditions, but information on use under daily practice conditions is required to confirm the effectiveness and safety of new management optio
Autor:
Aiko Osawa, Shinichiro Maeshima
Publikováno v:
European Neurology. 63:170-175
Objective: Unilateral spatial neglect (USN) is one of the major behavioral disturbances in patients with cerebral lesions and often impairs the patients’ independence in activities of daily living (ADL). Although many studies have addressed the mec
Publikováno v:
European Neurology. 55:198-203
The objective of the open-label, multicenter Migraine – Satisfaction with Treatment: Reality with Almogran® study was to assess efficacy, tolerability, and satisfaction with almotriptan 12.5 mg among migraineurs who were not achieving adequate res
Autor:
Hiroshi Kigawa, Yoshitake Hirano, Shinichiro Maeshima, Koji Takeda, Megumi Baba, Daisuke Nishio, Aiko Osawa
Publikováno v:
European neurology. 68(4)
Background: The purpose of this study was to clarify the effects of voluntary training with family participation in addition to conventional rehabilitation for stroke patients. Methods/Design: The subjects were 49 first-time stroke patients with seve
Publikováno v:
European neurology. 66(1)
Background/Aim: Stimulant medications can enhance mood and cognition in stroke rehabilitation, but human clinical trial results are inconclusive. We sought to prospectively study the effects of levodopa (LD) and/or methylphenidate (MPH) in combinatio
Autor:
A.J. Pilgrim
Publikováno v:
European Neurology. 31:295-299
The clinical development of sumatriptan has involved large international multicentre trials. To allow comparison of results obtained in a variety of clinical settings, great emphasis was placed on the use of consistent methodology across the programm
Publikováno v:
European neurology. 61(3)
Background: Tremor is one of the cardinal symptoms in Parkinson’s disease, but only few clinical studies have focussed on its therapy as the primary endpoint. One reason is the substantial fluctuation of tremor severity over time, which is difficul