Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fang Chen"'
Publikováno v:
European Journal of Pharmacology. 837:96-104
Transforming growth factor-β1 (TGF-β1)-induced epithelial to mesenchymal transition (EMT) and renal fibrosis plays critical role in the development and progression of diabetic nephropathy (DN). Our study aimed to determine the detailed roles of miR
Autor:
Yi-Shui Chen, Fen-fang Chen, Xin Zhang, Fang Peng, Yang yu Zhou, Qing-Peng Hu, Wei Feng, Xiang-Yi Huang, Hong-xia Yan
Publikováno v:
European Journal of Pharmacology. 912:174620
Background Epilepsy is a common chronic neurological disease. Recurrent seizures can cause irreversible brain damage. This study aimed to explore the regulation of Genistein on JAK2/STAT3 and Keap1/Nrf2 signaling pathway and the protective effects on
Publikováno v:
European Journal of Pharmacology. 906:174269
Icariin and icaritin, the major active components of Epimedii Genus, are considered as promising drugs with anti-inflammatory, anti-aging and neuroprotective effects. Our previous studies have demonstrated that icariin and icaritin can protect agains
Publikováno v:
European journal of pharmacology. 844
Cervical cancer (CC) is the fourth most frequent malignancy worldwide. MicroRNAs (miRNAs) can function as potential biomarkers or therapeutic targets in multiple cancers including CC. Our present study aimed to investigate the roles and downstream ta
Publikováno v:
European journal of pharmacology. 804
Naringin, a naturally flavanone glycoside, has been previously demonstrated to alleviate diabetic kidney disease by inhibiting oxidative stress and inflammatory reaction. However, the underlying mechanism of naringin in diabetic nephropathy (DN) has
Autor:
Xiang Chen, Ming-Xing Miao, Yungen Xu, Guoqing Gong, Yun-Zhan Li, Xin-Hui Wang, Qiu-fang Chen, Yourui Su, Zhen-Zhou Jiang, Ai-Dou Jiang, Shuang Cui, Mei-Ling Jiang
Publikováno v:
European journal of pharmacology. 781
The generation of thrombus is not considered as an isolated progression without other pathologic processes, which may also enhance procoagulant state. The purpose of this study was to assess whether HY023016, a novel dabigatran prodrug and an oral di