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Publikováno v:
European journal of pharmacology. 913
Nutraceuticals are principally extracted from natural products that are frequently safe and well-tolerated. Lycopene and berberine are natural plants with a wide range of beneficial effects including protective activities against metabolic disorders
Autor:
Nan Hu, Ming-Hui Ma, Zhi-Jie Sun, Ming Cao, Jin-Lai Gao, Wen-Feng Li, Xin-Rui Yang, Man Jiang, De-Li Dong, Yao Fu, Jing Zhao
Publikováno v:
European journal of pharmacology. 912
The heart is a high energy demand organ and enhancing mitochondrial function is proposed as the next-generation therapeutics for heart failure. Our previous study found that anthelmintic drug niclosamide enhanced mitochondrial respiration and increas
Publikováno v:
European journal of pharmacology. 912
Neuroinflammation contributes significantly to the pathogenesis of diabetic peripheral neuropathy (DPN). Quercetin reportedly exerts neuroprotective effects in DPN. Here, we aimed to evaluate the potential anti-inflammatory effects of quercetin in a
Publikováno v:
European journal of pharmacology. 911
Myrcene (Myr) has been reported to show neuroprotective effects in cerebral ischemia. In this research work, we investigated the Myr effect on neurobehavioural, and neuropathological alteration in mice induced by Aluminium trichloride (AlCl3) and D -
Autor:
Elena Reyes-Cuapio, Jocelyne Alcaraz-Silva, Jorge Carlos Ruiz-Ruiz, Eric Murillo-Rodríguez, Claudio Imperatori, Carla Quiroga, Astrid Coronado-Álvarez
Publikováno v:
European journal of pharmacology. 910
The use of cannabidiol (CBD), the non-psychotropic compound derived from Cannabis sativa, for therapeutic purposes is growing exponentially by targeting the management of multiple medical disorders, including metabolic-related diseases. Nevertheless,
Autor:
Klemencja Berghauzen-Maciejewska, Tomasz Lenda, Jolanta Konieczny, Maciej Wieczorek, Jerzy Pieczykolan, Krystyna Ossowska, Mikołaj Matłoka
Publikováno v:
European journal of pharmacology. 910
Phosphodiesterase 10A (PDE10A), the enzyme which catalyzes hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), is located almost exclusively in striatal γ-amino-butyric acid (GABA)ergic medium spiny neurons
Publikováno v:
European journal of pharmacology. 908
The antidepressant effect of curcumin-coated iron oxide nanoparticles (Cur-IONPs) was investigated in the current study using depression rat model induced by reserpine. IONPs were synthesized by curcumin as a reducing agent producing Cur-IONPs. Rats
Autor:
Mutsuyoshi Matsushita, Takahisa Yamada, Yoshinori Kosugi, Takeshi Ohta, Takashi Nakagawa, Takahiro Hata, Takafumi Kurimoto, Katsuya Deai, Atsuko Miyai, Yasuo Yamamoto, Isao Tamai
Publikováno v:
European Journal of Pharmacology. 895
Classic glucocorticoids have been prescribed for various inflammatory diseases, such as rheumatoid arthritis, due to their outstanding anti-inflammatory effects. However, glucocorticoids cause numerous unwanted side effects, including osteoporosis an
Autor:
Ayako Furugen, Fumi Kitaichi, Katsuya Narumi, Yoshitaka Saito, Masaki Kobayashi, Keisuke Okamoto, Hinata Ueda
Publikováno v:
European journal of pharmacology. 909
Cisplatin (CDDP) is a highly potent anticancer drug that is widely used in the treatment of several cancers. CDDP-induced nephrotoxicity (CIN) is one of the most significant adverse effects, and oxidative stress is thought to be one of the mechanisms
Autor:
Sayed A. Sayed, Hala O. El-Mesallamy, Marwa O. El-Derany, Sara A. Wahdan, Al-Aliaa M. Sallam, Rana K. El-Asfar, Ebtehal El-Demerdash
Publikováno v:
European journal of pharmacology. 908
Background and aim Tamoxifen (TAM) therapy has been associated with fatty liver diseases. Recently, multiple reports have also shown that TAM is related to cognitive impairment in patients with breast cancer. Luteolin, a natural flavonoid, has been t