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Autor:
Gareth L. Ackland, Alexander V. Gourine, Anna Hadjihambi, Anastassios Karagiannis, Shefeeq M. Theparambil
Publikováno v:
European Journal of Pharmacology
The effects of anaesthetic agents on brain energy metabolism may explain their shared neurophysiological actions but remain poorly understood. The brain lactate shuttle hypothesis proposes that lactate, provided by astrocytes, is an important neurona
Autor:
Misha F. Vrolijk, Antoon Opperhuizen, Aalt Bast, Paul M. H. Schiffers, Eugène H.J.M. Jansen, Guido R.M.M. Haenen
Publikováno v:
European Journal of Pharmacology, 746, 132-137. Elsevier Science
The food supplement quercetin is used as self-medication for prostate disorders and is known to induce vasorelaxation. The drug tamsulosin is used in the treatment of benign prostatic hyperplasia. A major side effect of tamsulosin is orthostatic hypo
Autor:
Kelly Mast, Edouard M. Bevers, Jef L. N. Wolfs, Marie-Claire Kleinegris, Ger H. Koek, Eveline H.C. Mestrom
Publikováno v:
European Journal of Pharmacology, 693(1-3), 1-6. Elsevier Science
Ribavirin in combination with interferon-alpha is the standard treatment for chronic hepatitis C, but often induces severe anemia forcing discontinuation of the therapy. Whereas suppression of bone marrow by interferon may impact on the production of
Autor:
Bert Schutte, Luc J.M. Nieland, Frans C. S. Ramaekers, Dick Terwel, Harry W.M. Steinbusch, Chris P. M. Reutelingsperger
Publikováno v:
European Journal of Pharmacology, 400, 400-400. Elsevier Science
CHP212 neuroblastoma cells were exposed to two different nitric oxide (NO) donors, S -nitroso- N -acetylpenicillamine and sodium nitroprusside. Apoptosis and necrosis were determined with flow cytometric analysis of annexin V binding and propodium io