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Autor:
Jason T. Lee, András Füredi, Oliver Langer, R. Michael van Dam, Divya Maheshwari, Theresa Falls, Pavitra Kannan, Gergely Szakács, Severin Mairinger, Sabina Dizdarevic, Jeffrey Collins, Thomas Wanek
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose Multidrug resistance (MDR) impedes cancer treatment. Two efflux transporters from the ATP-binding cassette (ABC) family, ABCB1 and ABCG2, may contribute to MDR by restricting the entry of therapeutic drugs into tumor cells. Although a higher