Zobrazeno 1 - 7
of 7
pro vyhledávání: '"64"'
Publikováno v:
European Journal of Immunology. 34:2119-2128
In the thymus, CD4+ or CD8+ single-positive (SP) thymocytes develop and mature by positive and negative selection or undergo "death by neglect". CD4+ or CD8+ SP then circulate to other lymphoid tissues. We have investigated the role of reactive oxyge
Publikováno v:
European Journal of Immunology. 32:1099-1108
L(d)- and K(b)-binding epitopes processed by murine dendritic cells (DC) pulsed with exogenous, particulate hepatitis B surface antigen (HBsAg) are presented to cytotoxic T lymphocytes (CTL). The specific and dose-dependent induction of IFN-gamma rel
Autor:
Richard J. DiPaolo, Emil R. Unanue
Publikováno v:
European Journal of Immunology. 31:3453-3459
We report a mouse model for the spontaneous development of autoimmune diabetes: the 3A9 T cell receptor (TCR) transgenic mouse, which contains T cells that recognize the 52 - 61 family of hen egg-white lysozyme (HEL) peptides in the context of MHC cl
Autor:
Jean-François Gauchat, Jean-Yves Bonnefoy, Yves Delneste, Giovanni Magistrelli, Nathalie Herbault, Amélie Benoit de Coignac, Pascale Jeannin
Publikováno v:
European Journal of Immunology. 29:3596-3602
CTLA-4, expressed by activated T cells, transduces an inhibitory signal. We show here that PCR amplification of the coding sequence of CTLA-4 in nonstimulated human T lymphocytes results in the amplification of two transcripts of 650 and 550 bp. Sequ
Autor:
Marco Cippitelli, Angela Santoni
Publikováno v:
European Journal of Immunology. 28:3017-3030
1Alpha,25-dihydroxyvitamin D3 [1,25-(OH)2D3] exerts several effects on the immune system, by regulating lymphocyte proliferation, differentiation of monocytes and secretion of cytokines as IL-2, granulocyte-macrophage colony-stimulating factor and IF
Autor:
Sarah M. Russell, Sheng Wei, Warren J. Leonard, Dewayne Ussery, Jin Hong Liu, Pearlie K. Epling-Burnette, Julie Y. Djeu, Federica Pericle
Publikováno v:
European Journal of Immunology. 25:291-294
Functional interleukin-2 receptors (IL-2R) on lymphocytes contain both IL-2R beta and gamma chains. Whereas constitutive expression of IL-2R beta has been found on monocytes, the expression of IL-2R gamma on these phagocytes has not been examined. We
Publikováno v:
European Journal of Immunology. 20:889-896
Immunological events are involved in the pathophysiology of chronic active hepatitis as indicated from the accumulation of T lymphocytes at the site of tissue damage. We generated T cell clones from liver biopsies of 3 patients with chronic active he