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of 60
pro vyhledávání: ''
Autor:
Anette S. B. Wolff, Beate Skinningsrud, Klaus Badenhoop, Anna L. Mitchell, Gesine Meyer, Dag E. Undlien, Marissa Penna-Martinez, William Ollier, Eystein S. Husebye, Simon H. S. Pearce, Corrado Betterle, Alberto Falorni
Publikováno v:
European Journal of Endocrinology. 184:373-381
Objective While vitamin D regulates immune cells, little is known about it in autoimmune Addison’s disease (AAD). We investigated the vitamin D status in AAD patients from five European populations to assess its deficiency. In addition, we studied
Autor:
Uberto Pagotto, Margherita Baccini, Alessia Fazzini, Flaminia Fanelli, Marco Mezzullo, Alessandra Gambineri, Carla Pelusi, Valentina Vicennati, Guido Di Dalmazi, Andrea Repaci
Publikováno v:
European Journal of Endocrinology. 182:459-471
Objective To evaluate the independent impact of age, obesity and metabolic risk factors on 13 circulating steroid levels; to generate reference intervals for adult men. Design Cross-sectional study. Methods Three hundred and fifteen adults, drug-free
Autor:
Michael A. Nauck, Juris J. Meier
Publikováno v:
European Journal of Endocrinology. 181:R211-R234
GLP-1, a peptide hormone secreted from the gut, stimulating insulin and suppressing glucagon secretion was identified as a parent compound for novel treatments of diabetes, but was degraded (dipeptidyl peptidase-4) and eliminated (mainly by kidneys)
Autor:
Jolique A van Ipenburg, Adrian Daly, Esther Donga, Aart-Jan van der Lely, Kay J Pieterman, Leo J. Hofland, Eva C Coopmans, Albert Beckers, Sebastian J C M M Neggers, Sebastiaan W F van Meyel
Publikováno v:
European Journal of Endocrinology, 181(2), K21-K27. Bioscientifica Ltd
Prolactinomas are the most commonly encountered pituitary adenomas in the clinical setting. While most can be controlled by dopamine agonists, a subset of prolactinomas are dopamine-resistant and very aggressive. In such tumors, the treatment of choi
Autor:
Patric J.D. Delhanty, Sebastian J C M M Neggers, Iain K. Haitsma, Eva C Coopmans, Alof H G Dallenga, Joseph A M J L Janssen, Aart Jan van der Lely, Ammar Muhammad
Publikováno v:
European Journal of Endocrinology, 179(5), 269-277. Bioscientifica Ltd
ObjectiveTo assess the efficacy and safety after 48 weeks of treatment with pasireotide long-acting-release (PAS-LAR) alone or in combination with pegvisomant in patients with acromegaly. In addition, we assessed the relation between insulin secretio
Autor:
Fabiana Pani, Clelia Madeddu, Valeria Pusceddu, Elena Massa, Matteo Massidda, Stefano Mariotti, Mario Scartozzi, Marco Puzzoni
Publikováno v:
European Journal of Endocrinology. 177:85-92
Objective Thyroid dysfunction has been reported during Regorafenib (Reg) administration, but no detailed study is presently available. Design Prospective, observational cohort study. Patients with documented metastatic colorectal cancer and progressi
Autor:
Ja Yoon Gu, Eun Sook Kim, Hyun Ju Yoo, Hyun Kyung Kim, Se Eun Han, Nam Hee Kim, Young Il Kim, Il Sung Nam-Goong
Publikováno v:
European Journal of Endocrinology. 176:583-589
BackgroundHyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extracellular traps (NET) has emerged as an important trigger of thrombosis, we hypothesized that the contact system
Autor:
Labrini Papanastasiou, Eva Kassi, Aglaia Zachaki, George P. Chrousos, Athina Markou, Ioannis I. Androulakis, Nick Voulgaris, George Piaditis, Theodora Kounadi, Gregory Kaltsas, Vaios Tsiavos
Publikováno v:
European Journal of Endocrinology. 175:21-28
Context Primary aldosteronism (PA) is the most common cause of endocrine hypertension that is diagnosed following a two-step process: an initial screening test, based on the serum aldosterone-to-renin ratio (ARR), followed by a relatively laborious a
Autor:
Ilona Fatorova, Petr Sadilek, Jitka Cepkova, Jaroslav Maly, Pavel Zak, Jiri Horacek, Ioannis Svilias, Jaroslav Vizda, Lukas Smolej
Publikováno v:
European Journal of Endocrinology. 172:537-542
ObjectiveWith increasing free thyroxine levels, a gradually rising risk of venous thromboembolism has been described in case–control studies. However, reports on the influence of thyroid hormones on haemostasis, while suggesting a hypercoagulable s
Autor:
Olaf M. Dekkers, E. P. M. Corssmit, Ellen Kapiteijn, E. N. Klein Klein Hesselink, D. Steenvoorden, Thera P. Links, van der Anouk Horst-Schrivers, Johan Lefrandt
Publikováno v:
European Journal of Endocrinology. 172:R215-R225
ContextMany tyrosine kinase inhibitors (TKIs) have been studied in patients with thyroid carcinoma (TC). However, the effect and toxicity of various TKIs in differentiated TC (DTC) and medullary TC (MTC) patients have not been directly compared. The