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Autor:
Valentina Gallina, Gian Paolo Rossi, Renzo De Toni, Teresa Maria Seccia, Matteo Vincenzi, Diego Miotto, Achille C. Pessina
Publikováno v:
European Journal of Endocrinology. 165:85-90
BackgroundAdrenal vein sampling (AVS) is the gold standard for identifying the surgically curable forms of primary aldosteronism. Dopamine modulates adrenocortical steroidogenesis and tonically inhibits aldosterone secretion via D2 receptor. However,
Publikováno v:
European Journal of Endocrinology. 160:657-665
ObjectivesPremature adrenarche (PA), the early rise in adrenal androgen (AA) production, can manifest with different clinical signs of androgen effect. Premature pubarche defined as appearance of pubic hair before the age of 8/9 years in girls/boys,
Autor:
Dorthe Cartier, Antoine Bennet, C. Regnier, Monique Plantavid, P. Caron, Françoise Parmentier, André Lacroix, Hervé Lefebvre, Delphine Vezzosi, Ph. Otal
Publikováno v:
European Journal of Endocrinology. 156:21-31
ACTH-independent macronodular adrenocortical hyperplasia (AIMAH) is rare and generally presents as a sporadic disease. We describe a familial case of AIMAH with in vivo and in vitro demonstration of aberrant 5-HT4 and vasopressin adrenal receptors. T
Publikováno v:
European Journal of Endocrinology. :613-618
OBJECTIVE: The antagonism of Agouti protein (AP) and Agouti-related protein on melanocortin receptors suggests an inhibitory role in the regulation of steroidogenesis. However, we have previously demonstrated that ectopic AP overexpression increased
Publikováno v:
European Journal of Endocrinology. :265-270
OBJECTIVE: Agouti protein (AP) and agouti-related protein with a similar sequence and action are endogenous antagonists of melanocortin receptors, implicated in the control of the hypothalamo-pituitary-adrenal (HPA) axis. Dominant mutation of the ago
Publikováno v:
European Journal of Endocrinology. :45-53
Objective: In chronic inflammatory diseases, serum levels of dehydroepiandrosterone (DHEA) sulfate (DHEAS) are low. Interestingly, several non-inflammatory diseases display similarly low levels of DHEAS which points to other inhibitory factors such a
Autor:
Kumiko Tsuboi, Masako Shimojo, Naoki Hiroi, Yukitaka Miyachi, Fumiatsu Yakushiji, Yusuke Shimizu, Hajime Ueshiba
Publikováno v:
European Journal of Endocrinology. :375-380
OBJECTIVE: To analyze activities of adrenal steroidogenic enzymes in type 2 diabetes mellitus, serum levels of 11 steroid hormones were measured simultaneously. SUBJECTS: We studied 130 patients with type 2 diabetes mellitus (74 men and 56 women betw
Publikováno v:
European Journal of Endocrinology. :238-245
OBJECTIVE: An increased response of 17-hydroxyprogesterone to ACTH stimulation has been observed in adrenal incidentaloma and linked to an impairment of either 21-hydroxylase or of 11beta-hydroxylase activity. To analyse this question further, we inv
Publikováno v:
European Journal of Endocrinology. 85:109-117
In 4 young healthy males, serum levels of 11-deoxycortisol (S), cortisol (F), 11-deoxycorticosterone (DOC) and corticosterone (B) were determined at short intervals after oral administration of 30 mg/kg of metyrapone (M) at midnight. 11-hydroxylase b