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Publikováno v:
European Journal of Clinical Pharmacology
Purpose Remifentanil has been shown to increase the bioavailability of nasally administered naloxone. The aim of this study was to explore the nature of this observation. Methods We analysed samples from three pharmacokinetic studies to determine the
Publikováno v:
European Journal of Clinical Pharmacology. 77:1679-1686
Acute coronary syndrome (ACS) carries a high mortality in Uygur populations. Percutaneous coronary intervention (PCI) is a safe treatment for patients with ACS. Clopidogrel reduces the risk for recurrent cardiovascular events after PCI; however, its
Publikováno v:
European Journal of Clinical Pharmacology. 77:1649-1663
The trial aimed to investigate the effectiveness of exogenous melatonin as an adjuvant to pregabalin for relief of pain in patients suffering from painful diabetic neuropathy (PDN). This randomized, double-blind, placebo-controlled trial was carried
Autor:
Mika Gissler, Maarit K. Leinonen, Heli Malm, Leena K. Saastamoinen, Maria Ellfolk, Sonja Kiuru-Kuhlefelt
Publikováno v:
European Journal of Clinical Pharmacology
Purpose To study if second-generation antipsychotic (S-GA) use during the first trimester of pregnancy is associated with an increased risk of major congenital malformations (MCM). Methods A population-based birth cohort study using national register
Autor:
Yuichi Kojima, Takako Miyazaki, Kazuhide Higuchi, Yuki Hirata, Yasuhiro Ueda, Shiro Nakamura, Hiroyuki Tsujimoto, Kazuki Kakimoto, Ryoji Koshiba, Toshihisa Takeuchi, Kazuhiro Ota, Naohiko Kinoshita, Yasuyoshi Tanaka, Hideki Tawa
Publikováno v:
European Journal of Clinical Pharmacology. 77:1639-1648
Low-dose aspirin (LDA) administration prevents cerebral infarction and myocardial infarction, but many studies found an association with mucosal injury. Proton-pump inhibitors (PPIs) can prevent gastric and duodenal mucosal damage, but they may exace
Autor:
Enrique Linden-Torres, Luis E. Simental-Mendía, Mario Simental-Mendía, Adriana Sánchez-García
Publikováno v:
European Journal of Clinical Pharmacology. 77:1705-1712
The aim of this meta-analysis of randomized controlled trials was to evaluate the effect of hydroxychloroquine on glucose control. Randomized controlled trials examining the impact of hydroxychloroquine on glycemic markers were searched in PubMed, We
Publikováno v:
European Journal of Clinical Pharmacology. 77:1523-1529
Previous studies have indicated an increased risk of gallbladder disease with hormonal contraceptives although with discordant results. The potential increased risk of gallbladder disease with hormonal contraceptives is concerning given that women ar
Publikováno v:
European Journal of Clinical Pharmacology. 77:1553-1561
The aim of this study was to explore patterns and long-term development in prescribing potentially inappropriate medication (PIM) according to the EU(7)-PIM list to elderly patients in Germany. We analysed anonymized German claims data. The study pop
Autor:
Maja Hellfritzsch, Bent Lind, Anna E. Engell, Tore Bjerregaard Stage, Andreas L.O. Svendsen, Anton Pottegård
Publikováno v:
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of Clinical Pharmacology, vol. 77, pp. 1435–1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of Clinical Pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of clinical pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of Clinical Pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of clinical pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Purpose: Concomitant use of vitamin K antagonists (VKA) and statins is frequent in cardiovascular patients. However, clinical guidelines on this drug combination are divergent. Therefore, we performed a systematic review to evaluate the effect of sta
Autor:
Rami Tadros, Lorraine Mackenzie, Michael D. Wiese, Patrick Russell, Craig Phillips, Aymen Ali Al-Qurain, Richard N. Upton, Michael S. Roberts, Desmond B. Williams
Publikováno v:
European Journal of Clinical Pharmacology. 77:1357-1368
Purpose Subcutaneous fentanyl injection is commonly prescribed to manage acute pain in older patients; however, there is a gap in the literature describing the pharmacokinetic parameters for this route of administration in this population. The aim of