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Publikováno v:
European Journal of Clinical Pharmacology. 77:1679-1686
Acute coronary syndrome (ACS) carries a high mortality in Uygur populations. Percutaneous coronary intervention (PCI) is a safe treatment for patients with ACS. Clopidogrel reduces the risk for recurrent cardiovascular events after PCI; however, its
Publikováno v:
European Journal of Clinical Pharmacology. 77:1649-1663
The trial aimed to investigate the effectiveness of exogenous melatonin as an adjuvant to pregabalin for relief of pain in patients suffering from painful diabetic neuropathy (PDN). This randomized, double-blind, placebo-controlled trial was carried
Autor:
Mika Gissler, Maarit K. Leinonen, Heli Malm, Leena K. Saastamoinen, Maria Ellfolk, Sonja Kiuru-Kuhlefelt
Publikováno v:
European Journal of Clinical Pharmacology
Purpose To study if second-generation antipsychotic (S-GA) use during the first trimester of pregnancy is associated with an increased risk of major congenital malformations (MCM). Methods A population-based birth cohort study using national register
Autor:
Yuichi Kojima, Takako Miyazaki, Kazuhide Higuchi, Yuki Hirata, Yasuhiro Ueda, Shiro Nakamura, Hiroyuki Tsujimoto, Kazuki Kakimoto, Ryoji Koshiba, Toshihisa Takeuchi, Kazuhiro Ota, Naohiko Kinoshita, Yasuyoshi Tanaka, Hideki Tawa
Publikováno v:
European Journal of Clinical Pharmacology. 77:1639-1648
Low-dose aspirin (LDA) administration prevents cerebral infarction and myocardial infarction, but many studies found an association with mucosal injury. Proton-pump inhibitors (PPIs) can prevent gastric and duodenal mucosal damage, but they may exace
Autor:
Enrique Linden-Torres, Luis E. Simental-Mendía, Mario Simental-Mendía, Adriana Sánchez-García
Publikováno v:
European Journal of Clinical Pharmacology. 77:1705-1712
The aim of this meta-analysis of randomized controlled trials was to evaluate the effect of hydroxychloroquine on glucose control. Randomized controlled trials examining the impact of hydroxychloroquine on glycemic markers were searched in PubMed, We
Publikováno v:
European Journal of Clinical Pharmacology. 77:1523-1529
Previous studies have indicated an increased risk of gallbladder disease with hormonal contraceptives although with discordant results. The potential increased risk of gallbladder disease with hormonal contraceptives is concerning given that women ar
Autor:
Maja Hellfritzsch, Bent Lind, Anna E. Engell, Tore Bjerregaard Stage, Andreas L.O. Svendsen, Anton Pottegård
Publikováno v:
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of Clinical Pharmacology, vol. 77, pp. 1435–1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of Clinical Pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of clinical pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of Clinical Pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Engell, A E, Svendsen, A L O, Lind, B S, Stage, T B, Hellfritzsch, M & Pottegård, A 2021, ' Drug-drug interactions between vitamin K antagonists and statins : a systematic review ', European Journal of clinical pharmacology, vol. 77, no. 10, pp. 1435-1441 . https://doi.org/10.1007/s00228-020-03074-w
Purpose: Concomitant use of vitamin K antagonists (VKA) and statins is frequent in cardiovascular patients. However, clinical guidelines on this drug combination are divergent. Therefore, we performed a systematic review to evaluate the effect of sta
Autor:
Sandrine Turpault, Joseph D. Ma, Edmund V. Capparelli, Lana Tran, Joseph S. Bertino, Angela D. M. Kashuba, Anne N. Nafziger, Mina Nikanjam
Publikováno v:
European Journal of Clinical Pharmacology. 77:1349-1356
S-warfarin is used to phenotype cytochrome P450 (CYP) 2C9 activity. This study evaluated S-warfarin limited sampling strategy with a population pharmacokinetic (PK) approach to estimate CYP2C9 activity in healthy adults. In 6 previously published stu
Sertraline concentrations in pregnant women are steady and the drug transfer to their infants is low
Autor:
Lars L. Gustafsson, Josefine Nasiell, Anton Pohanka, Mats Blennow, Margareta Blomdahl-Wetterholm, M. Hovstadius, Katarina Wide, Essi Heinonen
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Sertraline, a selective serotonin reuptake inhibitor (SSRI), is one of the most commonly used antidepressant during pregnancy. Plasma sertraline concentrations vary markedly between individuals, partly explained by variability in hepatic drug
Autor:
João Filipe Raposo, Ana Paula Martins, António Teixeira Rodrigues, Carla Torre, J.P. Guerreiro, Labib AL-Musawe, Helder Mota-Filipe
Publikováno v:
European Journal of Clinical Pharmacology. 77:1397-1407
To describe and assess the impact of polypharmacy, and its potential adverse reactions; serious clinically relevant drug-drug interactions (DDIs) and inappropriate medicines (PIMs) on glycemic target, and kidney function in a sample of older adults w