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Autor:
Yuichi Kojima, Takako Miyazaki, Kazuhide Higuchi, Yuki Hirata, Yasuhiro Ueda, Shiro Nakamura, Hiroyuki Tsujimoto, Kazuki Kakimoto, Ryoji Koshiba, Toshihisa Takeuchi, Kazuhiro Ota, Naohiko Kinoshita, Yasuyoshi Tanaka, Hideki Tawa
Publikováno v:
European Journal of Clinical Pharmacology. 77:1639-1648
Low-dose aspirin (LDA) administration prevents cerebral infarction and myocardial infarction, but many studies found an association with mucosal injury. Proton-pump inhibitors (PPIs) can prevent gastric and duodenal mucosal damage, but they may exace
Autor:
Enrique Linden-Torres, Luis E. Simental-Mendía, Mario Simental-Mendía, Adriana Sánchez-García
Publikováno v:
European Journal of Clinical Pharmacology. 77:1705-1712
The aim of this meta-analysis of randomized controlled trials was to evaluate the effect of hydroxychloroquine on glucose control. Randomized controlled trials examining the impact of hydroxychloroquine on glycemic markers were searched in PubMed, We
Autor:
Sandrine Turpault, Joseph D. Ma, Edmund V. Capparelli, Lana Tran, Joseph S. Bertino, Angela D. M. Kashuba, Anne N. Nafziger, Mina Nikanjam
Publikováno v:
European Journal of Clinical Pharmacology. 77:1349-1356
S-warfarin is used to phenotype cytochrome P450 (CYP) 2C9 activity. This study evaluated S-warfarin limited sampling strategy with a population pharmacokinetic (PK) approach to estimate CYP2C9 activity in healthy adults. In 6 previously published stu
Autor:
Joan Ramon Badia, Chantal Csajka, Alejandro Rodriguez, Dolors Soy, Carla Bastida, Mireia Llaurado-Serra, Ignacio Martin-Loeches, Marta Ulldemolins
Publikováno v:
European Journal of Clinical Pharmacology. 77:1169-1180
Ceftriaxone total and unbound pharmacokinetics (PK) can be altered in critically ill patients with septic shock and hypoalbuminemia receiving continuous veno-venous hemodiafiltration (CVVHDF). The objective of this study was to determine the dosing s
Autor:
Qi-Lin Ma, He-Li, Yin-Xiao Du, Kong-Xiang Zhu, Xiao-Ping Chen, Pei-Yuan Song, Li-Ming Peng, Mu-Peng Li
Publikováno v:
European Journal of Clinical Pharmacology. 77:359-368
Dual antiplatelet therapy with aspirin and clopidogrel is commonly used for coronary artery disease (CAD) patients undergoing percutaneous coronary intervention to prevent stent thrombosis and ischemic events. However, some patients show high on-trea
Publikováno v:
European Journal of Clinical Pharmacology, 1667-1673. Springer Verlag
ISSUE=12;STARTPAGE=1667;ENDPAGE=1673;ISSN=0031-6970;TITLE=European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology
ISSUE=12;STARTPAGE=1667;ENDPAGE=1673;ISSN=0031-6970;TITLE=European Journal of Clinical Pharmacology
European Journal of Clinical Pharmacology
Purpose Tacrolimus and everolimus are widely used to prevent allograft rejection. Both are metabolized by the hepatic cytochrome P450 (CYP) enzyme CYP3A4 and are substrate for P-glycoprotein (P-gp). Drugs influencing the activity or expression of CYP
Autor:
Jianping Zhang, Yulin Li, Zhiqiang Li, Yu Kong, Chunyu Wang, Linhai Sun, Xianjun He, Daorong Yang, Huanhuan Hu, Wanqing Dong, Yan Wang, Ming Zhao
Publikováno v:
European Journal of Clinical Pharmacology. 76:1517-1527
Dual antiplatelet therapy (DAT) with clopidogrel and aspirin is not suitable for clopidogrel resistance (CR) patients with aspirin intolerance. To investigate the prevalence of CR in patients with aspirin intolerance after ischemic stroke (IS) and to
Autor:
Vijay Patil, Amit Joshi, Kumar Prabhash, Murari Gurjar, Anand P. Patil, Deepali Patil, Vikram Gota, Manjunath Nookala, Bharati Shriyan, Vanita Noronha, Sadhana Kannan
Publikováno v:
European Journal of Clinical Pharmacology. 76:1427-1436
Patients of non–small cell lung cancer (NSCLC) with brain metastases have limited treatment options. High-dose erlotinib (HDE) and gefitinib (HDG) have been tried in the past. This study investigates the cerebrospinal fluid (CSF) disposition and sa
Autor:
Maarten Albersen, Roxanne Poncelet, Marcella Baldewijns, Greet Van De Sijpe, Benoit Beuselinck, Tine Van Nieuwenhuyse, Oliver Bechter, Jan Tack, Eduard Roussel, Isabel Spriet
Publikováno v:
European Journal of Clinical Pharmacology. 76:1273-1280
The aim of this study was to investigate the impact of acid suppressive therapy on clinical efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma (mRCC). A single-center retrospective study was carried out. Charts of mRCC
Publikováno v:
European Journal of Clinical Pharmacology
Purpose To analyze the clinical features and risk factors of tigecycline-associated hypofibrinogenaemia and study whether cefoperazone/sulbactam combined with tigecycline aggravates coagulopathy or hypofibrinogenaemia. Methods A retrospective case–