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Autor:
Laurent A. Decosterd, Thierry Buclin, Catia Marzolini, Monia Guidi, Chantal Csajka, Perrine Courlet, Susana Alves Saldanha, Matthias Cavassini, Marcel Stoeckle
Publikováno v:
European Journal of Clinical Pharmacology
European journal of clinical pharmacology, vol. 77, no. 7, pp. 979-987
European journal of clinical pharmacology, vol. 77, no. 7, pp. 979-987
Purpose Drug-drug interactions (DDIs) with antiretroviral drugs (ARVs) represent an important issue in elderly people living with HIV (PLWH). Amlodipine is a commonly prescribed antihypertensive drug metabolized by CYP3A4, thus predisposed to a risk
Autor:
Jonatan D. Lindh, Buster Mannheimer, Cecilia Fahlén Bergh, Henrik Falhammar, Jakob Skov, Jan Calissendorff
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Thiazide diuretics are the most common origin of drug-induced hyponatremia. However, population-based studies on clinical outcomes are lacking. We therefore explored the time course and absolute risk of thiazide-associated hospitalization due
Publikováno v:
European Journal of Clinical Pharmacology
Background Drug reaction with eosinophilia and systemic symptoms syndrome (DRESS) is a delayed infrequent potentially life-threatening idiosyncratic drug reaction. Aromatic anticonvulsants and allopurinol are the most frequent causative agents. Howev
Publikováno v:
European Journal of Clinical Pharmacology
Purpose To study the association between interacting drugs and bleeding or thromboembolism in atrial fibrillation outpatients treated with non-vitamin K antagonist oral anticoagulants (NOACs). Methods Population-based cohort study of outpatients trea
Publikováno v:
European Journal of Clinical Pharmacology
Purpose To investigate the comparative effectiveness of dopamine agonists and monoamine oxidase type-B (MAO-B) inhibitors available for treatment of Parkinson’s disease. Methods We performed a systematic literature search identifying randomized con
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Drug-drug interaction (DDI) potentials of lusutrombopag, a thrombopoietin receptor agonist, on the activity of cytochrome P450 (CYP) 3A and of cyclosporine, which inhibits P-glycoprotein and breast cancer resistance protein, on lusutrombopag
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Ceftazidime–avibactam is a novel β-lactam/β-lactamase inhibitor combination recently approved in Europe and the USA for the treatment of adults with hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), among other
Autor:
Susan M. Abdel-Rahman, Jonathan B. Wagner, Kayode Ogungbenro, Aleksandra Galetin, J. Steven Leeder
Publikováno v:
European Journal of Clinical Pharmacology
Ogungbenro, K, Wagner, J B, Abdel-Rahman, S, Leeder, J S & Galetin, A 2019, ' A population pharmacokinetic model for simvastatin and its metabolites in children and adolescents ', European journal of clinical pharmacology . https://doi.org/10.1007/s00228-019-02697-y, https://doi.org/10.1007/s00228-019-02697-y
Ogungbenro, K, Wagner, J B, Abdel-Rahman, S, Leeder, J S & Galetin, A 2019, ' A population pharmacokinetic model for simvastatin and its metabolites in children and adolescents ', European journal of clinical pharmacology . https://doi.org/10.1007/s00228-019-02697-y, https://doi.org/10.1007/s00228-019-02697-y
Purpose Poor adherence to dietary/behaviour modifications as interventions for hypercholesterolemia in paediatric patients often necessitates the initiation of statin therapy. The aim of this study was to develop a joint population pharmacokinetic mo
Autor:
Byung Won Yoo, Byung Hak Jin, J. M. Park, Min Soo Park, Jun Yeon Lee, Jae Soo Shin, Jung Hye Kim
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Ilaprazole, the latest proton pump inhibitor, can be used with clarithromycin and amoxicillin as a triple therapy regimen for eradicating Helicobacter pylori. The aim of this study was to evaluate pharmacokinetic drug interactions and safety
Publikováno v:
European Journal of Clinical Pharmacology
Purpose Methylenedioxymethamphetamine (MDMA, ecstasy) is used recreationally and frequently leads to sympathomimetic toxicity. MDMA produces cardiovascular and subjective stimulant effects that were shown to partially depend on the norepinephrine tra