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Autor:
Kazuma Kobayshi, Koichi Suyama, Hiroo Katsuya, Naoki Izawa, Yoshikazu Uenosono, Qingjiang Hu, Tetsuya Kusumoto, Hajime Otsu, Hiroyuki Orita, Hirofumi Kawanaka, Kazunori Shibao, Satoshi Koga, Mototsugu Shimokawa, Akitaka Makiyama, Hiroshi Saeki, Eiji Oki, Hideo Baba, Masaki Mori
Publikováno v:
European journal of cancer (Oxford, England : 1990). 166
The mainstream first-line chemotherapy for advanced/recurrent gastric cancer (ARGC) is combination therapy including platinum-based agents. With the progressive aging of the society, the incidence of gastric cancer in elderly patients is increasing.
Autor:
Alessio Amatu, Arianna Pani, Giorgio Patelli, Oscar M. Gagliardi, Marina Loparco, Daniele Piscazzi, Andrea Cassingena, Federica Tosi, Silvia Ghezzi, Daniela Campisi, Renata Grifantini, Sergio Abrignani, Salvatore Siena, Francesco Scaglione, Andrea Sartore-Bianchi
Publikováno v:
European Journal of Cancer
Background Patients with solid tumours have high COVID-19 mortality. Limited and heterogeneous data are available regarding the immunogenicity of SARS-CoV-2 mRNA vaccines in this population. Methods and Findings This is a prospective, single-center,
Autor:
Shinichiro Suzuki, Koji Haratani, Hidetoshi Hayashi, Yasutaka Chiba, Junko Tanizaki, Ryoji Kato, Seiichiro Mitani, Yusuke Kawanaka, Takashi Kurosaki, Yoshikazu Hasegawa, Takafumi Okabe, Kaoru Tanaka, Yusaku Akashi, Tomohiro Ozaki, Kazuto Nishio, Akihiko Ito, Kazuhiko Nakagawa
Publikováno v:
European journal of cancer (Oxford, England : 1990). 161
Tumour burden (TB) is implicated in resistance to programmed cell death-1/PD-L1 inhibitor (immune checkpoint inhibitor [ICI]) therapy. However, whether TB contributes to such resistance in non-small-cell lung cancer (NSCLC) has remained unknown.A tot
Autor:
Giovanni Randon, Rossana Intini, Chiara Cremolini, Elena Elez, Michael J. Overman, Jeeyun Lee, Paolo Manca, Francesca Bergamo, Filippo Pagani, Maria Antista, Valentina Angerilli, Francisco Javier Ros Montaña, Daniele Lavacchi, Alessandra Boccaccino, Giovanni Fucà, Silvia Brich, Laura Cattaneo, Matteo Fassan, Filippo Pietrantonio, Sara Lonardi
Publikováno v:
European journal of cancer (Oxford, England : 1990). 161
To unveil genomic and immunohistochemical expression profiles associated with primary resistance to EGFR/BRAF targeted therapy in patients with BRAF-mutated and microsatellite stable (MSS) metastatic colorectal cancer.In this multicenter case-control
Autor:
Emanuela Marcenaro, Carlotta Defferrari, Alberto Gozza, Nicoletta Sacchi, Mauro D'Amico, Matteo Clavarezza, Giacomo Siri, Nicoletta Provinciali, Oriana D’Ecclesiis, Andrea Decensi, Marco Musso, Isabella Cevasco, Nadia Menghini, Irene Maria Briata, Tania Buttiron Webber, Monica Magnani, Fortuna Paciolla, Sara Gandini, Raffaele De Palma, Martina Ugolini, Monica Boitano, Leonello Innocenti
Publikováno v:
European Journal of Cancer
Purpose Initial findings in patients with cancer suggest a lower seroconversion to SARS-COV-2 vaccination possibly related to myelo-immunosuppressive therapies. We conducted a prospective study to assess factors predicting poor seroconversion and adv
Autor:
Alexander Brobeil, Jakob Nikolas Kather, Tim Holland-Letz, Julia Höhn, Stefan Fröhling, Hermann Brenner, Sara Kuntz, Lennard Kiehl, Jenny Chang-Claude, Elizabeth Alwers, Christof von Kalle, Annette Kopp-Schneider, Titus J. Brinker, Eva Krieghoff-Henning, Michael Hoffmeister, Tanja B. Jutzi
Publikováno v:
European journal of cancer (Oxford, England : 1990). 157
Background Lymph node status is a prognostic marker and strongly influences therapeutic decisions in colorectal cancer (CRC). Objectives The objective of the study is to investigate whether image features extracted by a deep learning model from routi
Publikováno v:
European Journal of Cancer
Background Efficacy and safety data of COVID-19 vaccines among cancer populations have been limited; however, preliminary data from recent studies have emerged regarding their immunogenicity and safety in this population. In this review, we examined
Autor:
Kirsten B. Goldberg, Thomas U. Marron, Yutao Gong, Chieh J. Lee, Celina Ang, Pallavi S. Mishra-Kalyani, Tiziana Pressiani, Thoetchai Peeraphatdit, Lola Fashoyin-Aje, Anushi Bulumulle, Elad Sharon, Mahvish Muzaffar, Alessio Cortellini, Pei Chang Lee, Ahmed Kaseb, David J. Pinato, Steven Lemery, Uqba Khan, Anwaar Saeed, Sonal Paul, Yinghong Wang, Yehia I. Abugabal, Bo Yu, Tomi Jun, Sirish Dharmapuri, Nicola Personeni, Lorenza Rimassa, Antonio D'Alessio, Guo Wei, Marc R. Theoret, Musharraf Navaid, Anuhya Gampa, Richard Pazdur, Hannah Hildebrand, Abdul Rafeh Naqash, Neil Nimkar, Yi Hsiang Huang, David Szafron, Julie A. Schneider, Lorraine Pelosof, Dominik Bettinger, Anjana Pillai
Publikováno v:
European journal of cancer (Oxford, England : 1990). 157
Purpose The development of treatment-related adverse events (trAE) correlates favorably with clinical outcomes in multiple studies of patients receiving immune checkpoint inhibitors (ICI); however, this relationship is undefined in patients with hepa
Autor:
Tadeusz Dyba, M Bettio, Francesco Giusti, Giorgia Randi, Freddie Bray, Luciana Neamtiu, M. Flego, Jacques Ferlay, Anna Gavin, Nadya Dimitrova, N. Nicholson, Carmen Martos, Raquel Negrao Carvalho
Publikováno v:
European Journal of Cancer
Introduction Europe is an important focus for compiling accurate and up-to-date world cancer statistics owing to its large share of the world's total cancer burden. This article presents incidence and mortality estimates for 25 major cancers across 4
Autor:
Helmut Witzigmann, Christiane Jakob, Thomas Kittner, Erik Puffer, Joerg Zimmer, Dorothea Bleyl, Sigmar Stelzner, Matthias Kuhn, Soeren Torge Mees
Publikováno v:
European journal of cancer (Oxford, England : 1990). 159
Neoadjuvant treatment (nTx) for rectal cancer is commonly reserved for UICC stages II/III. Patients with stage I tumours (T1-2N0M0) are not candidates for nTx. The accuracy of treatment allocation depends on the precision of clinical staging, which i