Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Colin, P."'
Autor:
Ciarán, Campbell, Mark, McCormack, Sonn, Patel, Caragh, Stapleton, Dheeraj, Bobbili, Roland, Krause, Chantal, Depondt, Graeme J, Sills, Bobby P, Koeleman, Pasquale, Striano, Federico, Zara, Josemir W, Sander, Holger, Lerche, Wolfram S, Kunz, Kari, Stefansson, Hreinn, Stefansson, Colin P, Doherty, Erin L, Heinzen, Ingrid E, Scheffer, David B, Goldstein, Terence, O'Brien, David, Cotter, Samuel F, Berkovic, Sanjay M, Sisodiya, Norman, Delanty, Gianpiero L, Cavalleri
Publikováno v:
info:eu-repo/grantAgreement/EC/FP7/279062
OBJECTIVE: Levetiracetam (LEV) is an effective antiseizure medicine, but 10%-20% of people treated with LEV report psychiatric side-effects, and up to 1% may have psychotic episodes. Pharmacogenomic predictors of these adverse drug reactions (ADRs) h
Autor:
Kevin Power, Elizabeth Comerford, Mary Fitzsimons, Norman Delanty, Nisha Gangadharan, Marie T. Greally, Katherine A. Benson, Hany El-Naggar, Mark McCormack, Sinéad Heavin, Maire White, Colin P. Doherty, Brendan Dunleavey, Gianpiero L. Cavalleri
Publikováno v:
Epilepsia. 60:1670-1677
Objectives: Both clinical genomics and e-Health technology are changing the way medicine is being practiced. Although the basic clinical methodology of good medical care will remain unchanged, the combined power of genomics and electronic health reco
Autor:
Kevin Power, Colin P. Doherty, Norman Delanty, Hany El-Naggar, Veronica Lambert, Maire White, Brendan Dunleavy, Tim Jacquemard, Annette Breen, Mary Fitzsimons, Zita McCrea, Sean O'Donoghue
Publikováno v:
Epilepsia
Objectives The current coronavirus disease 2019 (COVID-19) pandemic stresses an urgency to accelerate much-needed health service reform. Rapid and courageous changes being made to address the immediate impact of the pandemic are demonstrating that th
Autor:
Anne Gehrmann, Sanjay M. Sisodiya, Anuranjan Anand, Nicholas W. Wood, John Lynch, Norman Delanty, Samuel F. Berkovic, Peter Kinirons, Sonia Gandhi, Nicole Soranzo, Parthasarathy Satishchandra, Thomas Sander, David Goldstein, Colin P. Doherty, John C. Mulley, Ingrid E. Scheffer, Ashish Kapoor, Gianpiero L. Cavalleri, Armin Heils, Nicole M. Walley, Chantal Depondt
Publikováno v:
Epilepsia. 48:706-712
Purpose: Although complex idiopathic generalized epilepsies (IGEs) are recognized to have a significant genetic component, as yet there are no known common susceptibility variants. It has recently been suggested that variation in the BRD2 gene confer
Autor:
Kevin Murphy, Sinead Maguire, Colin P. Doherty, Cathy Scanlon, Lisa Ronan, Norman Delanty, Mary Fitzsimons
Publikováno v:
Epilepsia. 48:211-219
Summary: Purpose: To introduce a measure of global cortical folding in epilepsy by using stereology. Subtle developmental abnormalities associated with temporal lobe epilepsy may encompass brain morphologic changes such as an aberrant degree of corti
Autor:
Mary Fitzsimons, Saud Alhusaini, Cathy Scanlon, Lisa Ronan, Christopher D. Whelan, Norman Delanty, Colin P. Doherty
Publikováno v:
Epilepsia. 54(9)
Summary The goal of this study was to characterize cerebral cortex thickness patterns in juvenile myoclonic epilepsy (JME). Surface-based morphometry (SBM) was applied to process brain magnetic resonance images acquired from 24 patients with JME and
Autor:
Saud, Alhusaini, Colin P, Doherty, Lena, Palaniyappan, Cathy, Scanlon, Sinead, Maguire, Paul, Brennan, Norman, Delanty, Mary, Fitzsimons, Gianpiero L, Cavalleri
Publikováno v:
Epilepsia. 53(6)
To date, magnetic resonance imaging (MRI)-based studies of the cerebral cortex in mesial temporal lobe epilepsy (MTLE) have focused primarily on investigating cortical volume and thickness. However, volume is a composite of surface area and thickness
Widespread cortical morphologic changes in juvenile myoclonic epilepsy: evidence from structural MRI
Autor:
Lisa, Ronan, Saud, Alhusaini, Cathy, Scanlon, Colin P, Doherty, Norman, Delanty, Mary, Fitzsimons
Publikováno v:
Epilepsia. 53(4)
Atypical morphology of the surface of the cerebral cortex may be related to abnormal cortical folding (gyrification) and therefore may indicate underlying malformations of cortical development (MCDs). Using magnetic resonance imaging (MRI)-based anal
Autor:
Colin P. Doherty, Jack Phillips, Kevin Murphy, Harsh W. Singh, John C. McHugh, Norman Delanty
Publikováno v:
Epilepsia. 48(2)
Summary: Purpose: Vagal nerve stimulation (VNS) is an adjunctive palliative therapy for refractory epilepsy. Effects of treatment are varied and some, such as the use of an external magnet for seizure termination, are unique to VNS. No accepted stand
Autor:
Norman Delanty, Gianpiero L. Cavalleri, Irene Reid, Patricia Logan, Colin P. Doherty, Peter Kinirons, Dierdre O'Rourke, B Liggan
Publikováno v:
Epilepsia. 47(2)
Summary: Purpose: The anticonvulsant vigabatrin (VGB) causes irreversible visual-field constriction in 19–92% of patients. It is unclear whether this correlates with dosing, and the natural history of the retinopathy remains obscure. We conducted a