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pro vyhledávání: '"59"'
Autor:
Liana M. Matson, Robyn B. Lee-Stubbs, Kari M. Haines, David Bibi, Cherish E. Ardinger, John H. McDonough, Emily N. Dunn, Meir Bialer
Publikováno v:
Epilepsia. 60:315-321
Objectives Children and adults are likely to be among the casualties in a civilian nerve agent exposure. This study evaluated the efficacy of valnoctamide (racemic-VCD), sec-butylpropylacetamide (racemic-SPD), and phenobarbital for stopping nerve age
Autor:
Frederic deBock, Alexis Fayd'herbe de Maudave, Chaitali Ghosh, Federica Bertaso, Julie Espallergues, Alexandre Milman, Leonie Runtz, Marion Toussenot, Benoit Girard, Nathalie C. Guérineau, Nicola Marchi, Jean-Marc Pascussi
Publikováno v:
Epilepsia
Epilepsia, Wiley, 2018, 59 (1), pp.123-134. ⟨10.1111/epi.13942⟩
Epilepsia, Wiley, 2018, 59 (1), pp.123-134. ⟨10.1111/epi.13942⟩
OBJECTIVE Available evidence points to a role of cytochrome P450 (Cyp) drug biotransformation enzymes in central nervous system diseases, including epilepsy. Deviations in drug pharmacokinetic profiles may impact therapeutic outcomes. Here, we ask wh