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Autor:
Steen Stender, Anna-Maria Andersson, Niels Jørgensen, Pal B. Szecsi, Jacob P. Thyssen, Hanne Frederiksen, Jørgen Holm Petersen, Ulla Nordström Joensen
Publikováno v:
Environment International, Vol 121, Iss, Pp 365-374 (2018)
Background: The filaggrin gene (FLG) encodes an epidermal protein, filaggrin, which is important for normal skin barrier functions. We previously showed that FLG loss-of-function mutation carriers have a higher internal exposure to some non-persisten
Autor:
Wenzhen Ge, Qingyang Zhu, Yuhan Zhou, Huijing Shi, Yunhui Zhang, Yingya Zhao, Yan Zhao, Bin Xia, Qi Song
Publikováno v:
Environment International, Vol 121, Iss, Pp 159-168 (2018)
Objective: Metabolomics may unravel global metabolic changes in response to environmental exposures and identify important biological pathways involved in the pathophysiology of childhood obesity. Phthalate has been considered an obesogen and contrib
Autor:
Neil J. Perkins, Kurunthachalam Kannan, Enrique F. Schisterman, Andrea Carmichael, Jenna R. Krall, Lindsey A. Sjaarda, Sunni L. Mumford, Anna Z. Pollack
Publikováno v:
Environment International, Vol 120, Iss, Pp 137-144 (2018)
Background Little is known about the associations of bisphenol A, chlorophenols, benzophenones, and parabens with reproductive hormone levels in women. Our goal was to evaluate the associations between repeated measures of these chemicals and their m
Autor:
Jerry L. Campbell, Winfried Kessler, Hermann Fromme, Harvey J. Clewell, Warwick A. Anderson, Peyton L. Ward, Martin B. Phillips, Matthew P. Longnecker, Miyoung Yoon
Publikováno v:
Environment International, Vol 113, Iss, Pp 91-99 (2018)
A higher body mass index (BMI) has been positively associated with the rate of excretion of di-2-ethylhexyl phthalate (DEHP) metabolites in urine in data from the National Health and Nutrition Examination Survey (NHANES), suggesting an association be
Autor:
Abby G. Wenzel, Michael S. Bloom, John W. Brock, Stephen E. Somerville, Lori Cruze, Elizabeth Ramsey Unal, John R. Kucklick, Celeste D. Butts, Rebecca J. Wineland, Roger B. Newman
Publikováno v:
Environment International, Vol 110, Iss, Pp 61-70 (2018)
Background: Select phthalates have antiandrogenic activity, which raises concern for adverse developmental outcomes given widespread exposure of pregnant women. Investigators have reported associations between maternal urinary phthalates and altered
Publikováno v:
Environment International, Vol 107, Iss, Pp 25-32 (2017)
Epidemiological studies have shown that thyroid hormone balances can be disrupted by chemical exposure. However, many association studies have often failed to consider multiple chemicals with possible common sources of exposure, rendering their concl
Autor:
Niels E. Skakkebæk, Pal B. Szecsi, Steen Stender, Jacob P. Thyssen, Ulla Nordström Joensen, Jørgen Holm Petersen, Hanne Frederiksen, Anne-Maria Andersson, Niels Jørgensen
Publikováno v:
Environment International, Vol 105, Iss, Pp 105-111 (2017)
Background: Filaggrin is an epidermal protein that is important for normal skin barrier functions. Up to 10% of Europeans and Asians carry filaggrin gene (FLG) loss-of function mutations that appear to facilitate trans-epidermal penetration of certai
Autor:
Michael D. McClean, Colleen M. Makey, Thomas F. Webster, Birgit Claus Henn, Elizabeth N. Pearce, Lewis E. Braverman, Emma V. Preston, Heather M. Stapleton
Publikováno v:
Environment International, Vol 101, Iss, Pp 158-164 (2017)
Triphenyl phosphate (TPHP) is a commonly used organophosphate flame retardant and plasticizer with widespread human exposure. Data on health effects of TPHP are limited. Recent toxicological studies suggest TPHP may alter thyroid function. We used re
Publikováno v:
Environment International, Vol 95, Iss, Pp 61-68 (2016)
Due to its toxicity as a carcinogen and wide distribution in the environment, arsenic (As) exposure in humans is of public concern globally. Many studies have manifested that As exposure induces cancers besides pathological effects in humans. Animal
Autor:
Alain Bousquet-Mélou, Nicole Picard-Hagen, Pierre-Louis Toutain, Marlène Z. Lacroix, Catherine Viguié, Glenn Gauderat, Véronique Gayrard, Tanguy Corbel, Pierre Mindeguia, Sylvie Puel
Publikováno v:
Environment International, Vol 86, Iss, Pp 52-59 (2016)
Environment International
Environment International, Elsevier, 2016, 86, pp.52-9. ⟨10.1016/j.envint.2015.10.006⟩
Environment International
Environment International, Elsevier, 2016, 86, pp.52-9. ⟨10.1016/j.envint.2015.10.006⟩
Previous studies in experimental animals have shown that maternal exposure to bisphenol A (BPA) during late pregnancy leads to high plasma concentrations of BPA glucuronide (BPAG) in fetus compared to mother due to the inability of BPAG to cross the