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Autor:
Michael J. MacDonald
Publikováno v:
Endocrinology. 129(3)
A water-soluble quinone, coenzyme Q0 (CoQ0), was shown to stimulate insulin release, and dicumarol, an inhibitor of quinone reductase, inhibited glucose-induced insulin release in pancreatic islets. Since this suggested that quinone reductase might p
Autor:
Michael J. MacDonald
Publikováno v:
Endocrinology. 108:1899-1902
The flavin contents of pancreatic islets and acinar tissue, whole pancreas, and liver of the rat were measured fluorometrically. Spectrofluorometric scanning of extracts of islets proved that they contained flavins. The spectra showed excitation peak